Job Description P16885 Confidence 99.93% Date Sat Jun 16 10:20:27 BST 2012 Rank 16 Aligned Residues 197 % Identity 26% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		531	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610
Predicted Secondary structure
Query SS confidence
Query Sequence		K	W	F	H	K	K	V	E	K	R	T	S	A	E	K	L	L	Q	E	Y	C	M	E	T	G	G	K	D	G	T	F	L	V	R	E	S	E	T	F	P	N	D	Y	T	L	S	F	W	R	S	G	R	V	Q	H	C	R	I	R	S	T	M	E	G	G	T	L	K	Y	Y	L	T	D	N	L	T	F	S	S	I
Query Conservation
Alig confidence																					.	.	.	.	.																																									.	.	.
Template Conservation																					.	.	.	.	.																																									.	.	.
Template Sequence		P	F	F	F	G	N	I	T	R	E	E	A	E	D	Y	L	V	Q	G	.	.	.	.	.	G	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	.	.	.	T	Y	A	I	A	G	G	R	T	H	A	S	P
Template Known Secondary structure		T	T			S	S												T	T	.	.	.	.	.	T			T	T								S	S	S	T	T									S	S	S										T	T	T	.	.	.					T	T	S			B	S	S
Template Predicted Secondary structure																					.	.	.	.	.																																									.	.	.
Template SS confidence
		14	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.						.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.				.	.	.	.	.	.	.	80	.	.	.	.	.
		611	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.														.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.		.	.	.	.	.	.	.	.	670	.	.	.	.	.	.
Predicted Secondary structure																														.	.	.	.	.	.	.	.	.	.	.	.	.																								.
Query SS confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.																								.
Query Sequence		Y	A	L	I	Q	H	Y	R	E	T	H	L	R	C	A	E	F	E	L	R	L	T	D	P	V	P	N	P	.	.	.	.	.	.	.	.	.	.	.	.	.	N	P	H	E	S	K	P	W	Y	Y	D	S	L	S	R	G	E	A	E	D	M	L	M	.	R	I	P	R	D	G	A	F	L	I	R	K	R	E	G
Query Conservation																														.	.	.	.	.	.	.	.	.	.	.	.	.																								.
Alig confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.																								.
Template Conservation
Template Sequence		A	D	L	C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K	T	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	N
Template Known Secondary structure									T	T			T	T	S	S	S				S	B					T	T															T	S	G	G	G		T	T																S	S				T	T								S	S
Template Predicted Secondary structure
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
		677	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.		700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.
Predicted Secondary structure																									.
Query SS confidence																									.
Query Sequence		S	D	S	Y	A	I	T	F	R	A	R	G	K	V	K	H	C	R	I	N	R	D	G	.	R	H	F	V	L	G	T	S	A	Y	F	E	S	L	V	E	L	V	S	Y	Y	E	K	H	S	L	Y	R	K	M	R	L	R	Y	P	V
Query Conservation																									.
Alig confidence																									.
Template Conservation
Template Sequence		N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C
Template Known Secondary structure		S	S									T	T											T	T	S					T	T	S			B	S										T	T			T	T	S	S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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