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Job DescriptionP42684
Confidence100.00%DateThu Apr 26 09:29:57 BST 2012
Rank186Aligned Residues251
% Identity25%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   286...290.........300.........310.........320.........330.........340.........350 .........360.
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Query Sequence  TDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGV. . . . CTLEPPFYIVT
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Template Sequence  RDITLLECVGKGRYGEVWRGSWQ. . GENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLIT
Template Known Secondary structure  TTTTT..T
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   206...210.........220........ .230.........240.........250.........260.........270.........280...
 
   362.......370.........380.........390.........400..... ....410.........420.........430...
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Query Sequence  EYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNF. . . . . . . . IHRDLAARNCLVGENHVVKVADFGLSRL
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Template Sequence  HYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
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B

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   284.....290......... 300.........310.........320.........330.........340.........350.........360
 
   434. ....440.........450.........460. ........470.........480.........490.
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Query Sequence  MT. . . GDTYTAHAGAKFPIKWTAPESLAYNT. . . . . . FSIKSDVWAFGVLLWEIATYGMSPYPGIDL. . . . . . . . . . . . .
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Template Sequence  HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDP
Template Known Secondary structure  TTTT








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   361........370.........380.........390.........400.........410...... ...420.........430.........
 
   492.......500......... 510.........520.........530.........540..
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Query Sequence  . . SQVYDLLEKGYRMEQPEG. . . . . . CPPKVYELMRACWKWSPADRPSFAETHQAFETM
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Template Sequence  SFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
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   440.........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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