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Job DescriptionP42684
Confidence100.00%DateThu Apr 26 09:29:57 BST 2012
Rank72Aligned Residues263
% Identity36%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   279280.........290.........300........ .310.........320 .........330.........340.........350...
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Query Sequence  DKWEMERTDITMKHKLGGGQYGEVYVGVWK. . . . KYSLTVAVKTLK. EDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTL
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCY.
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   840.........850.........860.........870.........880.........890.........900.........910........
 
   354.....360.........370.........380.........390.........400.........410.........420.........430...
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Query Sequence  EPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRL
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Template Sequence  . SNLKLIMEYLPYGSLRDYLQK. HKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKV
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   919920.........930......... 940.........950.........960.........970.........980.........990......
 
   434.....440.........450.........460.........470.........480........ .490.......
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Query Sequence  MTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPG. . . . . . . . . . . . . . . . IDLSQVYDL
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Template Sequence  LPQDKEKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL
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   1001........1010.........1020.........1030.........1040....... ..1050.........1060.........1070.........
 
   498.500.........510.........520.........530.........540.....
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Query Sequence  LEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHD
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Template Sequence  LKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQ
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   1082.......1090.........1100.........1110.........1120.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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