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Job DescriptionP42684
Confidence100.00%DateThu Apr 26 09:29:57 BST 2012
Rank68Aligned Residues260
% Identity35%Templatec3eygA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   279280.........290.........300........ .310.........320.........330.........340.........350....
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Query Sequence  DKWEMERTDITMKHKLGGGQYGEVYVGVWK. . . . KYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLE
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Template Sequence  DPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPH. . . IADLKKEIEILRNLYHENIVKYKGICTEN
Template Known Secondary structure 
TTS

GGG
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   866...870.........880.........890.........900.........910... ......920.........930.........940..
 
   355....360.........370.........380.........390.........400.........410.........420.........430....
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Query Sequence  PPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM
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Template Sequence  . GIKLIMEFLPSGSLKEYLPK. NKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAI
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TT
BTGG.GTTT

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SGGGTT


TT

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   951........960.........970 .........980.........990.........1000.........1010.........1020........
 
   435....440.........450.........460.........470.........480......... 490.........
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Query Sequence  TGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGI. . . . . . . . . . . . . . . DLSQVYDLLE
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Template Sequence  ETDKETVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLT. YCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLK
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   10291030.........1040.........1050.........1060.........1070.... .....1080.........1090.........1100.......
 
   500.........510.........520.........530.........540....
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Query Sequence  KGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH
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Template Sequence  EGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK
Template Known Secondary structure  TT





TT

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SSGGGS

TT

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   1110.........1120.........1130.........1140.........1150....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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