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Job DescriptionP42684
Confidence100.00%DateThu Apr 26 09:29:57 BST 2012
Rank214Aligned Residues266
% Identity36%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   281........290......... 300.........310......... 320.........330.........340.........350....
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Query Sequence  WEMERTDITMKHKLGGGQY. . . . GEVYVGVWKKYSLTVAVKTL. . KEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLE
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Template Sequence  FAGKTSSISDLKEVPRKNITLIRGLVYEGQVS. . PLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQS
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   1098.1100.........1110.........1120......... 1130.........1140.........1150.........1160.........1170.....
 
   355....360.........370........ .380.........390.........400.........410.........420.........
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Query Sequence  PPFYIVTEYMPYGNLLDYLRECNR. . . . . EEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFG
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Template Sequence  LPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIG
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   1190.........1200.........1210.........1220.........1230.........1240.........1250.........1260.........
 
   430.........440.........450.........460.........470.........480.........490.........500.........
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Query Sequence  LSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEG
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Template Sequence  DFGMARDIY. . . . . . AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKN
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   1270........ .1280.........1290.........1300.........1310.........1320.........1330.........1340...
 
   510.........520.........530.........540.........550....
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Query Sequence  CPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAE
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Template Sequence  CPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALP
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   1354.....1360.........1370.........1380.........1390........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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