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Job DescriptionP42684
Confidence100.00%DateThu Apr 26 09:29:57 BST 2012
Rank65Aligned Residues254
% Identity26%Templatec2j51A_
PDB info PDB header:transferaseChain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
Resolution2.1 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   284.....290.........300.........310.........320 .........330.........340.........350.........360..
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Query Sequence  ERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLK. EDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTE
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Template Sequence  PEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIE
Template Known Secondary structure  GGGTTTTTT


SSSTT


TTB

TT
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   30.........40.........50.........60.........70.........80.........90.........100.........
 
   363......370.........380.........390.........400.........410.........420.........430.........440..
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Query Sequence  YMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAH
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Template Sequence  FCAGGAVDAVMLELER. PLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRD
Template Known Secondary structure 

TTTS.


TT



SGGG
TTS



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S
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   110.........120..... ....130.........140.........150.........160.........170.........180........
 
   443......450....... ..460.........470.........480.........490.........500.. .......510.....
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Query Sequence  AGAKFPIKWTAPESL. . . . . AYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY. . RMEQPEGCPPKVY
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Template Sequence  S. FIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE. IEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFK
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S

TT

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STTTSSTTT.SS
TTTTS
GGGS




SSGGGS
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   189 190.........200.........210.........220.........230 .........240.........250.........260......
 
   516...520.........530.........540
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Query Sequence  ELMRACWKWSPADRPSFAETHQAFE
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Template Sequence  DFLKKCLEKNVDARWTTSQLLQHPF
Template Known Secondary structure  S
SSTTTS

TTSGG
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   267..270.........280.........290.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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