Job Description P42684 Confidence 100.00% Date Thu Apr 26 09:29:57 BST 2012 Rank 6 Aligned Residues 422 % Identity 43% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å

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		111	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.			150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure																																									.	.																																							.
Query SS confidence																																									.	.																																							.
Query Sequence		L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	Q	N	G	E	W	S	E	V	R	.	.	S	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	S	A	A	E	Y	L	L	.
Query Conservation																																									.	.																																							.
Alig confidence																													.	.											.	.																																							.
Template Conservation																													.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	.	.	E	E	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T							.	.				T	T							T	T	T								G	G	G				T	T	S	G	G	G	S	T	T			T	T											T
Template Predicted Secondary structure																													.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.			.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.
			188	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.						.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
Predicted Secondary structure		.																										.	.	.	.	.
Query SS confidence		.																										.	.	.	.	.
Query Sequence		.	S	S	L	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	L	S	I	S	L	R	.	.	.	.	.	Y	E	G	R	V	Y	H	Y	R	I	N	T	T	A	D	G	K	V	Y	V	T	A	E	S	R	F	S	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	V	T	T	L	H	Y
Query Conservation		.																										.	.	.	.	.
Alig confidence		.																										.	.	.	.	.
Template Conservation
Template Sequence		A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V
Template Known Secondary structure		S	T	T			T	T								S	S	S	T	T											T	T	T										B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S
Template Predicted Secondary structure
Template SS confidence
		139	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
		262	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	A	P	K	C	N	K	P	T	V	Y	G	V	S	P	I	H	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	V	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H
Query Conservation
Alig confidence														.	.	.	.																																	.
Template Conservation														.	.	.	.																																	.
Template Sequence		P	C	M	S	S	K	P	Q	K	P	W	E	.	.	.	.	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	.	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H
Template Known Secondary structure		B												.	.	.	.	T	T		S	B			G	G	G											T	T									T	T	.	T												S	S														T
Template Predicted Secondary structure														.	.	.	.																																	.
Template SS confidence
		219	220	.	.	.	.	.	.	.	.	.	230					.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.		.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.
		342	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	N	L	V	Q	L	L	G	V	C	T	L	E	P	P	F	Y	I	V	T	E	Y	M	P	Y	G	N	L	L	D	Y	L	R	E	C	N	R	E	E	V	T	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	D	L	A	A	R	N	C	L	V	G	E	N	H
Query Conservation
Alig confidence												.
Template Conservation												.
Template Sequence		D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L
Template Known Secondary structure		T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S			S	G	G	G					T	T
Template Predicted Secondary structure												.
Template SS confidence
		294	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.
		422	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	T	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	D	L	L	E	K	G
Query Conservation
Alig confidence													.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation													.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G
Template Known Secondary structure								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S																												T	T	T			S	S	T	T												T	T
Template Predicted Secondary structure													.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		373	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
		502	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	M	E	Q	P	E	G	C	P	P	K	V	Y	E	L	M	R	A	C	W	K	W	S	P	A	D	R	P	S	F	A	E	T	H	Q	A	F	E	T	M	F	H	D	S	S	I	S	E	E	V	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E	E	I	P
Template Known Secondary structure								T	T													T		S	S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		453	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.