|   |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
|
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | |
. | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Query Sequence |   |
P | Q | T | L | G | L | A | K | D | A | W | E | I | S | R | S | S | I | T | L | E | R | R | L | G | T | G | C | F | G | D | V | W | L | G | T | W | N | . |
G | S | T | K | V | A | V | K | T | L | K | P | G | T | . |
. |
. |
. |
M | S | P | K | A | F | L | E | E | A | Q | V | M | K | L | L | . |
R | H | D | K | L | V |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
| . |   |
|   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |
|
|
| Template Sequence |   |
S | Q | E | E | G | E | Y | F | N | V | P | V | P | P | L | T | D | F | N | F | L | M | V | L | G | K | G | S | F | G | K | V | M | L | S | E | R | K | G | T | D | E | L | Y | A | V | K | I | L | K | K | D | V | V | I | Q | D | D | D | V | E | C | T | M | V | E | K | R | V | L | A | L | P | G | K | P | P | F | L | T |
| Template Known Secondary structure |   |
| T | T | G | G | G | T |
|
|  |  |
|
|
|
| T | T |  |  |  |  |  |  | S | S | B | T | T | T | B |
|  |  |  |  |  |  | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
|
| T | T | B |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
|   |
|   |   |
320 | . | . | . | . | . | . | . | . | . | |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | L | Y | A | V | V | S | E | E | P | . |
I | Y | I | V | T | E | F | M | C | H | G | S | L | L | D | F | L | K | N | P | E | G | Q | D | L | R | L | P | Q | L | V | D | M | A | A | Q | V | A | E | G | M | A | Y | M | E | R | M | N | Y | I | H | R | D | L | R | A | A | N | I | L | V | G | E | R | L | A | C | K | I |
| Query Conservation |   |
  |
|   |
|   |   |   |   |   |   | . |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |   |   |
|   |
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|
| Template Sequence |   |
Q | L | H | S | C | F | Q | T | M | D | R | L | Y | F | V | M | E | Y | V | N | G | G | D | L | M | Y | H | I | Q | Q | V | G | . |
. |
R | F | K | E | P | H | A | V | F | Y | A | A | E | I | A | I | G | L | F | F | L | Q | S | K | G | I | I | Y | R | D | L | K | L | D | N | V | M | L | D | S | E | G | H | I | K | I |
| Template Known Secondary structure |   |
|  |  |  |
|
| B |
| S | S |  |  |  |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  |  |  | S | . | . | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |
|
|
|
|
| S | T | T |  |  |  |
| S | S | S |
|  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
405 | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | |
|
. | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
|   |
|   |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | D | F | G | L | A | R | L | I | K | D | D | E | Y | N | P | C | Q | G | S | K | F | P | I | K | W | T | A | P | E | A | A | L | F | G | R | F | T | I | K | S | D | V | W | S | F | G | I | L | L | T | E | L | I | T | K | G | R | I | P | Y | P | G | M | N | K | R | E | V | L | E | Q | V | E | Q | G | Y | H | M | P |
| Query Conservation |   |
  |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| Template Conservation |   |
  |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . |   |   |
| Template Sequence |   |
A | D | F | G | M | C | K | E | N | I | W | D | G | V | T | T | K | F | . |
. |
C | G | T | P | D | Y | I | A | P | E | I | I | A | Y | Q | P | Y | G | K | S | V | D | W | W | A | F | G | V | L | L | Y | E | M | L | A | . |
G | Q | A | P | F | E | G | E | D | E | D | E | L | F | Q | S | I | M | E | H | N | . |
V | A |
| Template Known Secondary structure |   |
|
|
| T | T |
|  |  |
|
|
| T | T |
|
| B |
|
| . | . |
| S |
| S | S | S |
|
|  |  |  |  | T |
|
|
| B | S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  | S | S |
| . |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
483 | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | |
|
. | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | |
. | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | |
. | . |
|   |
|   |   |
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 510 |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
| . | . | . | . | . |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
| Query Sequence |   |
C | P | P | G | C | P | A | S | L | Y | E | A | M | E | Q | T | W | R | L | D | P | E | E | R | P | T | . |
. |
. |
. |
. |
F | E | Y | L | Q | S |
| Query Conservation |   |
  |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
| . | . | . | . | . |   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |
|   |   |   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | P | K | S | M | S | K | E | A | V | A | I | C | K | G | L | M | T | K | H | P | G | K | R | L | G | C | G | P | E | G | E | R | D | I | K | E |
| Template Known Secondary structure |   |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | S | T | T |
| T | T |
| S | T | T |  |  |  |  |  |  | S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . |
|   |