|   |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
. | . | . | . | . | . | 290 | . | . | . | . | . | . | |
. | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
. | . | . | . | . | 320 | . | . | . | . | . | |
|
|
. | . | . | . | 330 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | S | I | T | L | E | R | R | L | G | T | G | C | F | G | D | V | W | L | G | T | W | N | . |
G | S | T | K | V | A | V | K | T | L | K | P | G | . |
T | M | S | P | K | A | F | L | E | E | A | Q | V | M | K | L | L | R | . |
H | D | K | L | V | Q | L | Y | A | V | V | . |
. |
. |
S | E | E | P | I | Y | I | V | T |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   | . |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   | . |
|   |
|
|
|   |
|   |
|   |   | . | . | . |   |   |   |   |   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |
| . | . | . | . | . | . | . |
|   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
| Template Sequence |   |
R | K | Y | E | L | V | K | K | I | . |
. |
. |
. |
. |
. |
. |
V | W | K | S | I | D | R | R | T | G | E | V | V | A | V | K | K | I | F | D | Q | N | S | T | D | A | Q | R | T | F | R | E | I | M | I | L | T | E | L | S | G | H | E | N | I | V | N | L | L | N | V | L | R | A | D | N | D | R | D | V | Y | L | V | F |
| Template Known Secondary structure |   |
T | T |  |  |  |  |  |
|
| . | . | . | . | . | . | . |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| T | T | B |
|
|  |  |  |  |  |  |
| T | T | S | S |
|  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
9 | 10 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
|   |
|   |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | F | M | C | H | G | S | L | L | D | F | L | K | N | P | E | G | Q | D | L | R | L | P | Q | L | V | D | M | A | A | Q | V | A | E | G | M | A | Y | M | E | R | M | N | Y | I | H | R | D | L | R | A | A | N | I | L | V | G | E | R | L | A | C | K | I | A | D | F | G | L | A | R | L | I | K | D | D | E | Y | N | P |
| Query Conservation |   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |   |   |
|   |
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   | . |   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | Y | M | E | . |
T | D | L | H | A | V | I | R | A | N | I | . |
. |
. |
L | E | P | V | H | K | Q | Y | V | V | Y | Q | L | I | K | V | I | K | Y | L | H | S | G | G | L | L | H | R | D | M | K | P | S | N | I | L | L | N | A | E | C | H | V | K | V | A | D | F | G | L | S | R | S | F | V | N | I | R | R | V | T |
| Template Known Secondary structure |   |
 |
|
| S | . |  |  |  |  |  |  |  |  |  | T |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
|  |  | S | S | S |
|
|
|
|
|
| Template Predicted Secondary structure |   |
 |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
91 | . | . | . | |
. | . | . | . | . | 100 | . | . | . | . | . | |
|
|
. | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |
|   |
|   |   |
415 | . | . | . | . | |
|
|
|
|
|
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
 |
|
|
|
| . | . | . | . | . | . |
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
C | Q | G | S | K | . |
. |
. |
. |
. |
. |
F | P | I | K | W | T | A | P | E | A | A | L | F | G | R | F | T | I | K | S | D | V | W | S | F | G | I | L | L | T | E | L | I | T | K | G | R | I | P | Y | P | G | M | N | K | R | E | V | L | E | Q | V | E | Q | G | Y | H | M | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
N | N | I | P | L | S | I | N | Y | V | A | T | R | W | Y | R | A | P | E | I | L | L | G | S | T | K | Y | T | K | G | I | D | M | W | S | L | G | C | I | L | G | E | I | L | C | . |
G | K | P | I | F | P | G | S | S | T | M | N | Q | L | E | R | I | I | G | V | I | D | F | P | S | N | E | D | V | E | S | I | Q | S |
| Template Known Secondary structure |   |
|
| G | G | G |
|
|
|
|
|
| G | G | G | G |
|
|  |  |  |  | T | T |
|
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | T | S |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
167 | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | P | P | G | C | P | A | S | L | Y | E | A | M | E | Q | T | W | R | L | D | P | E | E | R | P | T | F | E | Y | L | Q | S |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|   |
|
|
|   |
| Template Sequence |   |
P | F | A | K | T | M | I | E | S | L | K | E | K | V | E | K | R | D | I | F | T | K | W | K | N | L | L | L | K | I | N | P | K | A | D | C | N | E | E | A | L | D | L | L | D | K | L | L | Q | F | N | P | N | K | R | I | S | A | N | D | A | L | K |
| Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| S | S | G | G | G | S |
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
|   |