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Job DescriptionP09769
Confidence100.00%DateFri May 25 09:50:58 BST 2012
Rank161Aligned Residues250
% Identity27%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   261........270.........280.........290.........300.........310.........320...... ...330.....
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Query Sequence  SSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVS. . . . . EEPIYIVTE
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITH
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260.........270.........280....
 
   336...340.........350.........360.........370........ .380.........390.........400.......
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Query Sequence  FMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNY. . . . . . . . IHRDLRAANILVGERLACKIADFGLARLI
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Template Sequence  YHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMH
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B

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STT
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SGGG
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   285....290......... 300.........310.........320.........330.........340.........350.........360.
 
   408 .410.........420.........430.... .....440.........450.........460....
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Query Sequence  K. . . DDEYNPCQGSKFPIKWTAPEAALFGR. . . . . . FTIKSDVWSFGILLTELITKGRIPYPGMNK. . . . . . . . . . . . . .
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Template Sequence  SQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPS
Template Known Secondary structure  TTTT








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   362.......370.........380.........390.........400.........410...... ...420.........430.........440
 
   465....470.........480.. .......490.........500.........510.....
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Query Sequence  . REVLEQVEQGYHMPCPPG. . . . . . CPASLYEAMEQTWRLDPEERPTFEYLQSFLEDY
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Template Sequence  FEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   441........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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