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Job DescriptionP09769
Confidence100.00%DateFri May 25 09:50:58 BST 2012
Rank89Aligned Residues241
% Identity40%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   254.....260.........270.........280.........290.........300.........310.........320....... ..330..
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Query Sequence  DAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSE. EPIYI
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Template Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIK. . . . . . . EFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFI
Template Known Secondary structure  GGGB

GGGSTTSS
TTT

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TT


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   393......400.........410.........420.........430... ......440.........450.........460.....
 
   333......340.........350.........360.........370.........380.........390.........400.........410..
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Query Sequence  VTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEY
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Template Sequence  ITEYMANGCLLNYLREMRHR. FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . .
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TT
GGG
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TT


S

SGGG
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   473......480.........490.. .......500.........510.........520.........530.........540...
 
   413......420.........430.........440.........450.........460.........470.........480.........490..
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Query Sequence  NPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAME
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Template Sequence  . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
Template Known Secondary structure  .........GGG





TTS

TTTTS
TT





TTS
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   561........570.........580.........590.........600.........610.........620.........630.
 
   493......500.........510.........
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Query Sequence  QTWRLDPEERPTFEYLQSFLEDYFTSA
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Template Sequence  SCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


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   632.......640.........650........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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