|   |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
| Predicted Secondary structure |   |
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | K | D | A | W | E | I | S | R | S | S | I | T | L | E | R | R | L | G | T | G | C | F | G | D | V | W | L | G | T | W | N | G | . |
S | T | K | V | A | V | K | T | L | K | P | G | T | M | S | P | K | A | F | L | E | E | A | Q | V | M | K | L | L | R | H | D | K | L | V | Q | L | Y | A | V | V | S | E | E | P | I |
| Query Conservation |   |
  |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   | . |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   | . | . | . | . | . |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | T | V | D | D | Q | S | V | Y | P | K | A | L | R | D | E | Y | I | M | S | K | T | L | G | E | V | K | L | A | F | E | R | K | T | C | K | K | V | A | I | R | I | I | S | K | L | N | . |
. |
. |
. |
. |
V | E | T | E | I | E | I | L | K | K | L | N | H | P | C | I | I | K | I | K | N | F | F | D | A | E | D | Y |
| Template Known Secondary structure |   |
S | S | S | S |
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | T | T |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | S | S |
|
| Template Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
|   |
|   |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | |
|
|
. | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | I | V | T | E | F | M | C | H | G | S | L | L | D | F | L | K | N | P | E | G | Q | D | L | R | L | P | Q | L | V | D | M | A | A | Q | V | A | E | G | M | A | Y | M | E | R | M | N | Y | I | H | R | D | L | R | A | A | N | I | L | V | G | . |
. |
. |
E | R | L | A | C | K | I | A | D | F | G | L | A | R | L | I |
| Query Conservation |   |
  |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |   |   |
|   |
|   |
|
|   |   |   |
|
|
|   |   | . | . | . |   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
| Template Sequence |   |
Y | I | V | L | E | L | M | E | G | G | E | L | F | D | K | V | V | G | N | K | . |
. |
R | L | K | E | A | T | C | K | L | Y | F | Y | Q | M | L | L | A | V | Q | Y | L | H | E | N | G | I | I | H | R | D | L | K | P | E | N | V | L | L | S | S | Q | E | E | D | C | L | I | K | I | T | D | F | G | H | S | K | I | L |
| Template Known Secondary structure |   |
 |  |  |  |
|
|
| T | T |
| B |  |  |  |  |  |
| S | S |
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| T | T | T |  |  |  | S | S | S | S | S | S |
|
|  |  |  |
|
|
| S | S | S |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | |
|
. | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
|   |
|   |   |
408 | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | |
. | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | |
|
|
. | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
| Query Sequence |   |
K | D | D | E | Y | N | P | C | Q | G | S | K | F | P | I | K | W | T | A | P | E | A | A | L | F | G | R | F | T | I | K | S | D | V | W | S | F | G | I | L | L | T | E | L | I | T | K | G | R | I | P | Y | P | G | . |
M | N | K | R | E | V | L | E | Q | V | E | Q | G | Y | H | M | P | C | P | . |
. |
. |
P | G | C |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
| . | . | . |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | E | T | S | L | M | R | P | . |
. |
. |
. |
. |
. |
. |
. |
T | Y | L | A | P | E | V | L | V | A | G | Y | N | R | A | V | D | C | W | S | L | G | V | I | L | F | I | C | L | S | . |
G | Y | P | P | F | S | E | H | R | T | Q | V | S | L | K | D | Q | I | T | S | G | K | Y | N | F | I | P | E | V | W | A | E | V |
| Template Known Secondary structure |   |
T |  |  |
| T | T |
|
| . | . | . | . | . | . | . | . |
|
|
|
| S | T | T | T |
|
|
|
| S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S |
|
|
|
| S | S | S | S |
|  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  | T | T | S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
376 | . | . | . | 380 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | |
. | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . |
|   |
|   |   |
484 | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | A | S | L | Y | E | A | M | E | Q | T | W | R | L | D | P | E | E | R | P | T | F | E | Y | L | Q | S |
| Query Conservation |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|   |
|   |
| Template Sequence |   |
S | E | K | A | L | D | L | V | K | K | L | L | V | V | D | P | K | A | R | F | T | T | E | E | A | L | R |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
456 | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
|   |