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Job DescriptionP09769
Confidence100.00%DateFri May 25 09:50:58 BST 2012
Rank42Aligned Residues257
% Identity33%Templatec3eygA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   254.....260.........270.........280... ......290.........300.........310.........320........
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Query Sequence  DAWEISRSSITLERRLGTGCFGDVWLGTWN. . . . . GSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEE
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Template Sequence  DPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLK. . . PHIADLKKEIEILRNLYHENIVKYKGICTEN
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GGG
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T


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   866...870.........880.........890.........900.........910. ........920.........930.........940..
 
   329330.........340.........350.........360.........370.........380.........390.........400........
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Query Sequence  PIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIK
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Template Sequence  GIKLIMEFLPSGSLKEYLPKN. KNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIE
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TT
BTGGG.TTT

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SGGGTT


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   951........960.........970. ........980.........990.........1000.........1010.........1020.........
 
   409410.........420.........430.........440.........450......... 460.........470...
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Query Sequence  DDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPY. . . . . . . . . . . . . . . PGMNKREVLEQVEQ
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Template Sequence  TDKETVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLT. YCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKE
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   1030.........1040.........1050.........1060.........1070.... .....1080.........1090.........1100........
 
   474.....480.........490.........500.........510.....
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Query Sequence  GYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDY
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Template Sequence  GKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEAL
Template Known Secondary structure  T





TT

T

SSGGGS

TT
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   1111........1120.........1130.........1140.........1150..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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