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Job DescriptionP09769
Confidence100.00%DateFri May 25 09:50:58 BST 2012
Rank110Aligned Residues257
% Identity24%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   259260.........270.........280... ......290.... .....300.........310.........320......... 330..
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Query Sequence  SRSSITLERRLGTGCFGDVWLGTWN. GSTKVAVKTLK. . . . PGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEP. IYI
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYF
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
   333......340.........350.........360.........370.........380.........390.........400.........410..
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Query Sequence  VTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEY
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Template Sequence  GLSYAKNGELLKYIRKIG. . SFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . .
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   158.160.........170..... ....180.........190.........200.........210.........220.........230
 
   413......420.........430.........440.........450.........460.........470.........480.........490..
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Query Sequence  NPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAME
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Template Sequence  . . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVE
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   242.......250.........260.........270....... ..280.........290........ .300.........310....
 
   493......500.........510 .........520.........
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Query Sequence  QTWRLDPEERPTFEYLQS. . . . . . . . FLEDYFTSAEPQYQPGDQT
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Template Sequence  KLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT
Template Known Secondary structure  TTS
SSTTSSTTSGGGTTSGGGTT

GGGGGGS





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   315....320.........330.........340.........350.........
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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