Job Description P09769 Confidence 100.00% Date Fri May 25 09:50:58 BST 2012 Rank 3 Aligned Residues 450 % Identity 42% Template c2fo0A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase Resolution 2.27 Å

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		63	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	G	F	L	D	S	G	T	I	R	G	V	S	G	I	G	V	T	L	F	I	A	L	Y	D	Y	E	A	R	T	E	D	D	L	T	F	T	K	G	E	K	F	H	I	L	N	N	T	E	G	D	W	W	E	A	R	S	L	S	S	G	K	T	G	C	I	P	S	N	Y	V	A	P	V	D	S	I	Q	A	E
Query Conservation
Alig confidence																																																											.
Template Conservation																																																											.
Template Sequence		A	R	W	N	K	E	N	L	L	A	G	P	S	E	N	D	P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	.	T	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S	L	E	K	H
Template Known Secondary structure							T	T	T	T			G	G	G	S		T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S						.		T	T							G	G	G				T	T	S	G	G	G	S
Template Predicted Secondary structure																																																											.
Template SS confidence
		65	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.		.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.
		143	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	W	Y	F	G	K	I	G	R	K	D	A	E	R	Q	L	L	S	P	G	N	P	Q	G	A	F	L	I	R	E	S	E	T	T	K	G	A	Y	S	L	S	I	R	D	W	D	Q	T	R	G	D	H	V	K	H	Y	K	I	R	K	L	D	M	G	G	Y	Y	I	T	T	R	V	Q	F	N	S	V	Q	E	L
Query Conservation
Alig confidence																		.	.																											.	.	.	.	.
Template Conservation																		.	.																											.	.	.	.	.
Template Sequence		S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	.	.	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	.	.	.	.	.	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L
Template Known Secondary structure		T	T														T	.	.	S	S	S		T	T								S	S	S	T	T									.	.	.	.	.	T	T											T	T	S				S	S	T	T			B	S	S
Template Predicted Secondary structure																		.	.																											.	.	.	.	.
Template SS confidence
		145	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160			.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.						.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.
		223	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.				.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.		.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure																															.	.	.																																		.
Query SS confidence																															.	.	.																																		.
Query Sequence		V	Q	H	Y	M	E	V	N	D	G	L	C	N	L	L	I	A	P	C	T	I	M	K	P	Q	T	L	G	L	.	.	.	A	K	D	A	W	E	I	S	R	S	S	I	T	L	E	R	R	L	G	T	G	C	F	G	D	V	W	L	G	T	W	N	G	.	S	T	K	V	A	V	K	T	L	K	P	G	T	M
Query Conservation																															.	.	.																																		.
Alig confidence																															.	.	.																																		.
Template Conservation
Template Sequence		V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M
Template Known Secondary structure										T	T	S	S	S															S	S	S		S	S	T	T			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T										T	T	S
Template Predicted Secondary structure
Template SS confidence
		218	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.		.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.
Predicted Secondary structure																															.
Query SS confidence																															.
Query Sequence		S	P	K	A	F	L	E	E	A	Q	V	M	K	L	L	R	H	D	K	L	V	Q	L	Y	A	V	V	S	E	.	E	P	I	Y	I	V	T	E	F	M	C	H	G	S	L	L	D	F	L	K	N	P	E	G	Q	D	L	R	L	P	Q	L	V	D	M	A	A	Q	V	A	E	G	M	A	Y	M	E	R	M	N
Query Conservation																															.
Alig confidence																															.
Template Conservation
Template Sequence		E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N
Template Known Secondary structure																			T	T	B									S	S	S	S									T	T		B								S		T	T	T	S																						T	T
Template Predicted Secondary structure
Template SS confidence
		298	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.
		378	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	I	H	R	D	L	R	A	A	N	I	L	V	G	E	R	L	A	C	K	I	A	D	F	G	L	A	R	L	I	K	D	D	E	Y	N	P	C	Q	G	S	K	F	P	I	K	W	T	A	P	E	A	A	L	F	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	I	T	K	G	R	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S
Template Known Secondary structure					S			S	G	G	G					G	G	G							T	T						S	S							T	T					G	G	G																													T	T	S
Template Predicted Secondary structure
Template SS confidence
		378	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.
		458	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520
Predicted Secondary structure
Query SS confidence
Query Sequence		P	Y	P	G	M	N	K	R	E	V	L	E	Q	V	E	Q	G	Y	H	M	P	C	P	P	G	C	P	A	S	L	Y	E	A	M	E	Q	T	W	R	L	D	P	E	E	R	P	T	F	E	Y	L	Q	S	F	L	E	D	Y	F	T	S	A	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S	S
Template Known Secondary structure		S	S	T	T												T	T							T	T													T		S	S	G	G	G	S												T	S	S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		458	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520