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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank266Aligned Residues235
% Identity24%Templatec3ttjA_
PDB info PDB header:transferase/transferase inhibitorChain: A: PDB Molecule:mitogen-activated protein kinase 10; PDBTitle: crystal structure of jnk3 complexed with cc-359, a jnk inhibitor for2 the prevention of ischemia-reperfusion injury
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   336...340.........350.........360.........370..... ....380.........390.........400...... .
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Query Sequence  NLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGT. EKADTEEMMREAQIMHQLDNPYIVRLIGVCQ. . . . . . . A
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Template Sequence  KRYQNLKPIGSGAQGIVCAAYDAVLDR. . NVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEF
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   62.......70.........80........ .90.........100.........110.........120.........130.........
 
   408.410.........420.........430.........440.........450.........460.........470.........480.......
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Query Sequence  EALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALG
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Template Sequence  QDVYLVMELMDANLCQVIQME. . . . LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLASFMM
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   140.........150.........160 .........170.........180.........190.........200.........210.....
 
   488.490.........500.........510.........520.........530.........540.........550...
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Query Sequence  ADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIE. . . . . . . . . . . . . .
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Template Sequence  VTR. . . . . . . . . . . . . YYRAPEVILGMGYKENVDIWSVGCIMGEMVR. HKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL
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   225.. ..230.........240.........250........ .260.........270.........280.........290
 
   554.....560.........570.........580.........590
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . QGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVE
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Template Sequence  QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDAL
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   291........300.........310.........320.........330.........340.........350....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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