|   |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | |
|
|
. | . | . | . | 410 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
| Query Sequence |   |
N | L | L | I | A | D | I | E | L | G | C | G | N | F | G | S | V | R | Q | G | V | Y | R | M | R | K | K | Q | I | D | V | A | I | K | V | L | K | Q | G | T | E | K | A | D | T | E | E | M | M | R | E | A | Q | I | M | H | Q | L | D | N | P | Y | I | V | R | L | I | G | V | C | . |
. |
. |
Q | A | E | A | L | M | L |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   | . | . | . |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |
|
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
E | R | V | E | D | L | F | E | Y | E | G | C | K | V | G | H | V | Y | K | A | K | R | K | D | G | K | D | D | K | D | Y | A | L | K | Q | I | E | G | T | G | I | S | M | . |
. |
. |
S | A | C | R | E | I | A | L | L | R | E | L | K | H | P | N | V | I | S | L | Q | K | V | F | L | S | H | A | D | R | K | V | W | L |
| Template Known Secondary structure |   |
|
|  |  |  |  |  |  |
| S | S |
|
|
|
|  |  |  |  |  |  |  | S | S | S | S |
|
|
|
|  |  |  |  |  |
| S | S | S | S |
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|
|
|  |  |  |  |  | T | T | T | T |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 |
|   |
|   |   |
413 | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | |
|
|
|
. | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | M | E | M | A | G | G | G | P | L | H | K | F | L | V | G | K | R | E | E | I | P | V | S | N | V | A | E | L | L | H | Q | V | S | M | G | M | K | Y | L | E | E | K | N | F | V | H | R | D | L | A | A | R | N | V | L | L | V | N | R | H | . |
. |
. |
. |
Y | A | K | I | S | D | F | G | L | S | K | A | L | G | A |
| Query Conservation |   |
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   | . | . | . | . |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |
| Template Sequence |   |
L | F | D | Y | A | E | H | D | L | W | H | I | I | K | F | H | R | A | S | K | L | P | R | G | M | V | K | S | L | L | Y | Q | I | L | D | G | I | H | Y | L | H | A | N | W | V | L | H | R | D | L | K | P | A | N | I | L | V | M | G | E | G | P | E | R | G | R | V | K | I | A | D | M | G | F | A | R | V | T | F | W |
| Template Known Secondary structure |   |
 |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
| G | G | G |  |  |  |
|
| S | S | T | T | T | T |
|  |  |  |
|
| T | T |
|
|
|
|
|
| T |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . |
|   |
|   |   |
489 | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 550 | . | . | . | . | . | . | . | |
|
|
|
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
| Query Sequence |   |
D | D | S | Y | Y | T | A | R | S | A | G | K | W | P | L | K | W | Y | A | P | E | C | I | N | F | R | K | F | S | S | R | S | D | V | W | S | Y | G | V | T | M | W | E | A | L | S | Y | G | Q | K | P | Y | K | K | M | K | . |
. |
. |
. |
. |
. |
. |
G | P | E | V | M | A | F | I | E | Q | G | K | R | . |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |
| . | . | . | . |
| Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
| Template Conservation |   |
  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | A | P | E | L | L | L | G | A | R | H | Y | T | K | A | I | D | I | W | A | I | G | C | I | F | A | E | L | L | T | . |
S | E | P | I | F | H | C | R | Q | N | P | Y | H | H | D | Q | L | D | R | I | F | N | V | M | G | F | P | A | D | K | D | W | E |
| Template Known Secondary structure |   |
T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  | T | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| T | T | T |
| G |
| Template Predicted Secondary structure |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
199 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | E | C | P | P | E | C | P | P | E | L | Y | A | L | M | S | D | C | W | I | Y | K | W | E | D | R | P | D | F | L | T | V | E | Q | R | M | R | A | C | Y | Y | S | L | A | S | K | V | E | G | P | P |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |
|
|   |
|   | . | . | . |
|   |
|
|   |
| . | . | . | . | . |   |   |   |   |   |
| Template Sequence |   |
D | I | K | K | M | P | E | H | S | T | L | M | K | D | F | R | R | N | T | Y | T | N | C | S | L | I | K | Y | M | E | K | H | K | V | K | P | D | S | K | A | F | H | L | L | Q | K | L | L | T | M | D | P | I | K | R | I | T | S | E | Q | A | . |
. |
. |
M | Q | D | P | Y | F | . |
. |
. |
. |
. |
L | E | D | P | L |
| Template Known Secondary structure |   |
G | G | G | G | S | T | T |  |  |  |  |  |  |  |
|
| G | G | G | G | T | T |
|
|  |  |  |  |  |  | T | T | T |
|
| T | T | S |  |  |  |  |  |  |  |  |  | S |
| S | S | G | G | G | S |
|
|  |  |  |  | . | . | . |  | T | S | G | G | G | . | . | . | . | . | T | S | S | S |
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . | . |  |
|
|  |  |  | . | . | . | . | . |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
269 | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
|
|
330 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 340 |
|   |
|   |   |
609 | 610 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | S | T | Q | K | A | E | A | A |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |
| Template Sequence |   |
P | T | S | D | V | F | A | G | C |
| Template Known Secondary structure |   |
|
| S | S | T | T | T | T | S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|   |   |
341 | . | . | . | . | . | . | . | . |
|   |