|   |   |
338 | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | I | A | D | I | E | L | G | C | G | N | F | G | S | V | R | Q | G | V | Y | R | M | R | K | K | Q | I | D | V | A | I | K | V | L | K | Q | G | T | E | K | A | D | T | E | E | M | M | R | E | A | Q | I | M | H | Q | L | D | N | P | Y | I | V | R | L | I | G | V | C | Q | A | E | A | L | M | L | V | M | E | M | A |
| Query Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   |   | . | . | . | . | . | . |   |
|
|
|
|   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
F | T | L | G | R | M | L | G | K | G | E | F | G | S | V | R | E | A | Q | L | V | . |
. |
. |
. |
. |
. |
K | V | A | V | K | M | L | S | S | D | . |
. |
. |
. |
. |
I | E | E | F | L | R | E | A | A | C | M | K | E | F | D | H | P | H | V | A | K | L | V | G | V | S | L | R | S | I | P | M | V | I | L | P | F | M |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |  |  |  |  |  |  |
|
|  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |
|  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
508 | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 530 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . |
|   |
|   |   |
418 | . | 420 | . | . | . | . | . | |
|
. | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | G | G | P | L | H | K | F | . |
. |
L | V | G | K | R | E | E | I | P | V | S | N | V | A | E | L | L | H | Q | V | S | M | G | M | K | Y | L | E | E | K | N | F | V | H | R | D | L | A | A | R | N | V | L | L | V | N | R | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | G | A | D | D | S | Y | Y | T | A |
| Query Conservation |   |
  |   |
|
|
|   |   |   | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
K | H | G | D | L | H | A | F | L | L | A | S | R | I | P | F | N | L | P | L | Q | T | L | V | R | F | M | V | D | I | A | C | G | M | E | Y | L | S | S | R | N | F | I | H | R | D | L | A | A | R | N | C | M | L | A | E | D | M | T | V | C | V | A | D | F | G | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
T | T |
| B |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
|
| S | G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
597 | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
496 | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | S | A | G | K | W | P | L | K | W | Y | A | P | E | C | I | N | F | R | K | F | S | S | R | S | D | V | W | S | Y | G | V | T | M | W | E | A | L | S | Y | G | Q | K | P | Y | K | K | M | K | G | P | E | V | M | A | F | I | E | Q | G | K | R | M | E | C | P | P | E | C | P | P | E | L | Y | A | L | M | S | D | C |
| Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|
| Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
P | V | K | W | L | A | L | E | S | L | A | D | N | L | Y | T | V | H | S | D | V | W | A | F | G | V | T | M | W | E | I | M | T | R | G | Q | T | P | Y | A | G | I | E | N | A | E | I | Y | N | Y | L | I | G | G | N | R | L | K | Q | P | P | E | C | M | E | E | V | Y | D | L | M | Y | Q | C |
| Template Known Secondary structure |   |
. | . | . | . | . | . |
| G | G | G |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| T | T | T | T |
|
| G | G | G |  |  |  |  |  |  | T | T |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
685 | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . |
|   |
|   |   |
576 | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
W | I | Y | K | W | E | D | R | P | D | F | L | T | V | E | Q | R | M | R | A | C | Y | Y | S |
| Query Conservation |   |
  |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|
|   |
|
| Template Sequence |   |
W | S | A | D | P | K | Q | R | P | S | F | T | C | L | R | M | E | L | E | N | I | L | G | H |
| Template Known Secondary structure |   |
T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
759 | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . |
|   |