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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank194Aligned Residues230
% Identity27%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   331........340.........350.........360.........370.........380.........390.........400...... ...
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Query Sequence  FLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQ. AEA
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGR. . YYAMKILK. . . . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHDR
Template Known Secondary structure  T


TTSTTTTT

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   112.......120.........130.........140... ......150. ........160.........170.........180.
 
   410.........420.........430.........440.........450..... ....460.........470.........480........
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Query Sequence  LMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEK. NFVHRDLAARNVLLVNRHYAKISDFGLSKALGA
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Template Sequence  LCFVMEYANGGELFFHLSRERV. FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE. . .
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   223......230.........240.... .....250.........260.........270.........280.........290........
 
   489490.........500.........510.........520.........530.........540.........550.........560........
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Query Sequence  DDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPEL
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Template Sequence  . . . . . . . . . . . . . . PEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEA
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   313......320.........330.........340.... .....350.........360..... ....370......
 
   569570.........580... ......590
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Query Sequence  YALMSDCWIYKWEDR. . . . . PDFLTVE
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Template Sequence  KSLLSGLLKKDPKQRLGGGSEDAKEIM
Template Known Secondary structure  T
SSTTTSTT
STTT
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   377..380.........390.........400...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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