Job Description P43403 Confidence 100.00% Date Thu Apr 26 09:45:10 BST 2012 Rank 58 Aligned Residues 266 % Identity 34% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		329	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.			.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Predicted Secondary structure																																.	.
Query SS confidence																																.	.
Query Sequence		K	L	F	L	K	R	D	N	L	L	I	A	D	I	E	L	G	C	G	N	F	G	S	V	R	Q	G	V	Y	R	.	.	M	R	K	K	Q	I	D	V	A	I	K	V	L	K	Q	G	T	E	K	A	D	T	E	E	M	M	R	E	A	Q	I	M	H	Q	L	D	N	P	Y	I	V	R	L	I	G	V	C	Q
Query Conservation																																.	.
Alig confidence																																.	.
Template Conservation
Template Sequence		D	P	T	V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L	Y	H	E	H	I	I	K	Y	K	G	C	C	E
Template Known Secondary structure								G	G	G											S	S										T	T	S	S	S												S	S																						T	T	B
Template Predicted Secondary structure
Template SS confidence
		888	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.
		407	.				.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.
Predicted Secondary structure				.	.	.
Query SS confidence				.	.	.
Query Sequence		A	E	.	.	.	A	L	M	L	V	M	E	M	A	G	G	G	P	L	H	K	F	L	V	G	K	R	E	E	I	P	V	S	N	V	A	E	L	L	H	Q	V	S	M	G	M	K	Y	L	E	E	K	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	N	R	H	Y	A	K	I	S	D	F	G	L	S
Query Conservation				.	.	.
Alig confidence				.	.	.																						.	.
Template Conservation																												.	.
Template Sequence		D	A	G	A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	.	.	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A
Template Known Secondary structure			T	T	T	T										T	T		B					G	G	G	S	.	.																								T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure																												.	.
Template SS confidence
		968	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.			.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.
		484	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.																.	.	.	.	.	.	.
Predicted Secondary structure																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	A	L	G	A	D	D	S	Y	Y	T	A	R	S	A	G	K	W	P	L	K	W	Y	A	P	E	C	I	N	F	R	K	F	S	S	R	S	D	V	W	S	Y	G	V	T	M	W	E	A	L	S	Y	G	Q	K	P	Y	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	M	K	G	P	E	V
Query Conservation																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence								.	.	.	.																																										.							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation								.	.	.	.																																										.
Template Sequence		K	A	V	P	E	G	.	.	.	.	H	E	Y	R	V	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q	G	Q	M	T	V	L	R	L
Template Known Secondary structure						T	T	.	.	.	.				B						G	G	G								S		B																			T	.	T	T		G	G	G	S											S	T	T	G	G	G
Template Predicted Secondary structure								.	.	.	.																																										.
Template SS confidence
		1046	.	.	.	1050	.					.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
		549	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	A	F	I	E	Q	G	K	R	M	E	C	P	P	E	C	P	P	E	L	Y	A	L	M	S	D	C	W	I	Y	K	W	E	D	R	P	D	F	L	T	V	E	Q	R	M	R	A	C	Y	Y	S	L	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	E	L	L	E	R	G	E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	E	N	L	I	P	I	L	K	T	V	H	E	K	Y	Q
Template Known Secondary structure							T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1125	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions