Job Description P43403 Confidence 100.00% Date Thu Apr 26 09:45:10 BST 2012 Rank 186 Aligned Residues 244 % Identity 20% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		335	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.							.	.	.	.	400	.	.	.	.	.		.	.
Predicted Secondary structure																																																															.	.	.	.	.	.											.
Query SS confidence																																																															.	.	.	.	.	.											.
Query Sequence		D	N	L	L	I	A	D	I	E	L	G	C	G	N	F	G	S	V	R	Q	G	V	Y	R	M	R	K	K	Q	I	D	V	A	I	K	V	L	K	Q	G	T	E	K	A	D	T	E	E	M	M	R	E	A	Q	I	M	H	Q	L	D	N	.	.	.	.	.	.	P	Y	I	V	R	L	I	G	V	C	.	Q	A
Query Conservation																																																															.	.	.	.	.	.											.
Alig confidence																													.	.										.	.																						.	.	.	.	.	.											.
Template Conservation																													.	.										.	.
Template Sequence		A	Y	R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	K	V	H	.	.	Q	H	V	A	L	K	M	V	R	.	.	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T	F	R
Template Known Secondary structure		T	T	T										S	S	S									T	T	T	T	.	.										.	.	S																				T	T		T	T	S		S		B										T
Template Predicted Secondary structure																													.	.										.	.
Template SS confidence
		146	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.			.	.	.	.	.	.	.	180	.			.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
		408	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.			.	.	.	.	.	.	480	.	.	.	.	.
Predicted Secondary structure																																																																				.	.
Query SS confidence																																																																				.	.
Query Sequence		E	A	L	M	L	V	M	E	M	A	G	G	G	P	L	H	K	F	L	V	G	K	R	E	E	I	P	V	S	N	V	A	E	L	L	H	Q	V	S	M	G	M	K	Y	L	E	E	K	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	N	R	H	.	.	Y	A	K	I	S	D	F	G	L	S	K	A
Query Conservation																																																																				.	.
Alig confidence																																																																				.	.
Template Conservation
Template Sequence		N	H	I	C	M	T	F	E	L	L	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S	S	C	Y
Template Known Secondary structure		T												B								T	T	T																										T				S			S	G	G	G				S	S	T	T	S									T	T
Template Predicted Secondary structure
Template SS confidence
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.
		486	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																												.	.	.	.	.	.
Query SS confidence																																																																												.	.	.	.	.	.
Query Sequence		L	G	A	D	D	S	Y	Y	T	A	R	S	A	G	K	W	P	L	K	W	Y	A	P	E	C	I	N	F	R	K	F	S	S	R	S	D	V	W	S	Y	G	V	T	M	W	E	A	L	S	Y	G	Q	K	P	Y	K	K	M	K	G	P	E	V	M	A	F	I	E	Q	G	K	R	M	E	.	.	.	.	.	.
Query Conservation																																																																												.	.	.	.	.	.
Alig confidence												.	.	.	.	.	.	.																																	.																									.	.	.	.	.	.
Template Conservation												.	.	.	.	.	.	.																																	.
Template Sequence		E	H	Q	R	V	Y	T	I	Q	S	.	.	.	.	.	.	.	R	F	Y	R	A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L	D
Template Known Secondary structure		T	T									.	.	.	.	.	.	.	G	G	G								T	B				T																	.	S	S		S	S			S	S
Template Predicted Secondary structure												.	.	.	.	.	.	.																																	.
Template SS confidence
		302	.	.	.	.	.	.	.	310	.								.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.		.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
																																																			560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	C	P	P	E	C	P	P	E	L	Y	A	L	M	S	D	C	W	I	Y	K	W	E	D	R	P	D	F	L	T	V	E
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	S	K	R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	K	Q	C	L	E	W	D	P	A	V	R	M	T	P	G	Q	A	L
Template Known Secondary structure		T	B	T	T					B					B	T	T	S																T	T						S	T	T		S						T	T	T														T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		375	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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