Return to main results Retrieve Phyre Job Id

Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank139Aligned Residues240
% Identity37%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   329330.........340.........350.........360.........370.........380.........390.........400..... ..
Predicted Secondary structure 


























.
Query SS confidence 












































































.

Query Sequence  KLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC. QA
Query Conservation                 

 
 

 
             



 
              
  

  
 




 
 
  .  
Alig confidence 




























...











.........























.

Template Conservation      
          

 
 

 
 
   ...     



 

.........    

  
  
 




         
Template Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKW. . . RGQYDVAIKMIK. . . . . . . . . EFIEEAKVMMNLSHEKLVQLYGVCTKQ
Template Known Secondary structure  GGGB

GGGSTTSS
...TTT

.........

TT


TTB


SS
Template Predicted Secondary structure 





...



.........












Template SS confidence 















































































   393......400.........410.........420. ........430... ......440.........450.........460
 
   408.410.........420.........430.........440.........450.........460.........470.........480.......
Predicted Secondary structure 
































Query SS confidence 















































































Query Sequence  EALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALG
Query Conservation      

 
    


   
                 


 

 


   






  



     


 




    
Alig confidence 











































































....
Template Conservation       
        
                                                      
 
    ....
Template Sequence  RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . .
Template Known Secondary structure  SS


TT
GGG


TT


S

SGGG
TT







....
Template Predicted Secondary structure 













































....
Template SS confidence 















































































   468.470.........480.........490.........500.........510.........520.........530.........540...
 
   488.490.........500.........510.........520.........530.........540.........550.........560.......
Predicted Secondary structure 






































Query SS confidence 















































































Query Sequence  ADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPE
Query Conservation                
    


 
     
  







 
 
  
 
  
            
    
   
   
  
Alig confidence  ...............
































































Template Conservation  ...............                  

 
 
    

 
                 
            
  
Template Sequence  . . . . . . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEK
Template Known Secondary structure  ...............GGG





TTS

TTTTS
TT





TTS
Template Predicted Secondary structure  ...............











































Template SS confidence 















































































   561........570.........580.........590.........600.........610.........620.....
 
   568.570.........580.........590.........
Predicted Secondary structure 






Query SS confidence 































Query Sequence  LYALMSDCWIYKWEDRPDFLTVEQRMRACYYS
Query Conservation     
   
    
  


   
   
      
Alig confidence 































Template Conservation     

  

  

  


  


  
  

  
Template Sequence  VYTIMYSCWHEKADERPTFKILLSNILDVMDE
Template Known Secondary structure  TT
SSGGGS

Template Predicted Secondary structure 







Template SS confidence 































   626...630.........640.........650.......
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions