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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank48Aligned Residues260
% Identity35%Templatec3eygA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   329330.........340.........350........ .360.........370.........380.........390.........400......
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Query Sequence  KLFLKRDNLLIADIELGCGNFGSVRQGVYR. . MRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQ
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Template Sequence  DPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLK. . . . . PHIADLKKEIEILRNLYHENIVKYKGICT
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TTS

GGG
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TTSSS
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   866...870.........880.........890.........900.........910. ........920.........930.........940
 
   407..410.........420.........430.........440.........450.........460.........470.........480......
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Query Sequence  AEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKAL
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Template Sequence  ENGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAI
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TT
BTGGGTTT

TT
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SGGGTT


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   946...950.........960.........970.........980.........990.........1000.........1010.........1020.....
 
   487..490.........500.........510.........520.........530.........540 .........550.
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Query Sequence  GADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPY. . . . . . . . . . . . . . . KKMKGPEVMAF
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Template Sequence  ETDKETVKDDRDSP. . VFWYAPECLMQSKFYIASDVWSFGVTLHELLT. YCDSDSSPMALFLKMIGPTHGQMTVTRLVNT
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TT



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   10291030.........1040.. .......1050.........1060.........1070.... .....1080.........1090.........1100.....
 
   552.......560.........570.........580.........590......
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Query Sequence  IEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRAC
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Template Sequence  LKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEAL
Template Known Secondary structure  TT





TT

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SSGGGS

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   1108.1110.........1120.........1130.........1140.........1150..
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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