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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank82Aligned Residues253
% Identity26%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   329330.........340.........350.........360.........370..... ....380.........390.........400.......
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Query Sequence  KLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGT. EKADTEEMMREAQIMHQLDNPYIVRLIGVCQA
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . . . . VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK
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B

TT

TTSSS.....

SSS

TT


TTB


S
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   448.450.........460.........470......... 480.........490.........500.........510.........520..
 
   408.410.........420.........430.........440.........450.........460.........470.........480.......
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Query Sequence  EALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALG
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Template Sequence  PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL.
Template Known Secondary structure  SS


SS
BTS




TT
B
S

SGGGTTT


TT
B

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   523......530.........540.........550.........560.........570.........580.........590.........600.
 
   488.490.........500.........510..... ....520.........530.........540....... ..550.........
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Query Sequence  ADDSYYTARSAGKWPLKWYAPECINFRK. . . FSSRSDVWSYGVTMWEALSYGQKPYKKMKGPE. VMAFIEQGKRME. . . .
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Template Sequence  . . . . . . . . . . . . SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSK
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TT

TT
SS


S.SS
TTTT


TS



GGG
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   614.....620.........630.........640.........650. ........660.........670.........680
 
   560.........570.........580.........590.........600
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Query Sequence  CPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSL
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Template Sequence  VRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL
Template Known Secondary structure  S
TTS
T
SSGGGS

T
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   681........690.........700.........710.........720.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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