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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank254Aligned Residues228
% Identity26%Templatec3alnB_
PDB info PDB header:transferaseChain: B: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 4; PDBTitle: crystal structure of human non-phosphorylated mkk4 kinase domain2 complexed with amp-pnp
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   320.........330.........340.........350.........360.........370..... ....380.........390........
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Query Sequence  SDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGT. EKADTEEMMREAQIMHQLDNPYI
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Template Sequence  SGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQ. . IMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYI
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   84.....90.........100.........110.........120...... ...130.........140.........150.........160.
 
   399400..... ....410.........420......... 430.........440.........450..... ....460.........470...
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Query Sequence  VRLIGVC. QAEALMLVMEMAGGGPLHKFLVGK. . . REEIPVSNVAELLHQVSMGMKYLEEK. NFVHRDLAARNVLLVNRH
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Template Sequence  VQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSG
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   162.......170.........180.........190.........200.........210.........220.........230.........240.
 
   474.....480.........490.........500.........510.........520.........530.........540.........550...
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Query Sequence  YAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIE
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Template Sequence  NIKLCDFGIS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . GQLYDVRSDVWSLGITLYELAT. GRFPYPDPP. . . . . . . . .
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   242.......250. ........260.........270... ......280..
 
   554.....560.........570.........580.........
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Query Sequence  QGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTV
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Template Sequence  . QLSNSEEREFSPSFINFVNLCLTKDESKRPKYKEL
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   327..330.........340.........350.........360.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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