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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank172Aligned Residues253
% Identity34%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   344.....350.........360.........370.........380.........390.........400..... ....410.........420..
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Query Sequence  LGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC. QAEALMLVMEMAGGGPL
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Template Sequence  IRGLAFGEVYEGQV. . . . . PLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILMELMAGGDL
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   11191120.........1130.. .......1140.........1150.........1160.........1170.........1180.........1190...
 
   423..... .430.........440.........450.........460.........470.... .....480.........490...
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Query Sequence  HKFLVG. . . . . . KREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHY. . . AKISDFGLSKALGADDSYY
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Template Sequence  KSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYR. . . . .
Template Known Secondary structure  T


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   1205....1210.........1220.........1230.........1240.........1250.........1260.........1270.........
 
   494.....500.........510.........520.........530.........540.........550.........560.........570...
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Query Sequence  TARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMS
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Template Sequence  . . GGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMT
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   1286...1290.........1300.........1310.........1320.........1330.........1340.........1350.........1360...
 
   574.....580.........590.........600........
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Query Sequence  DCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPP
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Template Sequence  QCWQHQPEDRPNFAIILERIEYCTQDPDVINTALP
Template Known Secondary structure  T
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   1364.....1370.........1380.........1390........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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