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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank117Aligned Residues240
% Identity23%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   333......340.........350.........360.........370..... ....380.........390.........400...... ...
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Query Sequence  KRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGT. . EKADTEEMMREAQIMHQLDNPYIVRLIGVCQ. AEA
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Template Sequence  KRPEDFKFGKILGEGSFSTVVLARELATSR. . EYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEK
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GGG
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   77..80.........90.........100...... ...110.........120.........130.........140.........150....
 
   410.........420.........430.........440.........450.........460.........470.........480.........
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Query Sequence  LMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGAD
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Template Sequence  LYFGLSYAKNGELLKYIRKIGS. FDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLFVG
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TT
BSSS.

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   155....160.........170...... ...180.........190.........200.........210.........220.........230...
 
   490.........500.........510.........520.........530.........540.........550.........560.........
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Query Sequence  DSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELY
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Template Sequence  T. . . . . . . . . . . . AQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKAR
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   245 ....250.........260.........270....... ..280.........290........ .300.........310
 
   570.........580.........
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Query Sequence  ALMSDCWIYKWEDRPDFLTV
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Template Sequence  DLVEKLLVLDATKRLGCEEM
Template Known Secondary structure  TTS
SSTTSSTTSGGG
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   311........320.........330
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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