|   |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | R | D | N | L | L | I | A | D | I | E | L | G | C | G | N | F | G | S | V | R | Q | G | V | Y | R | M | R | K | K | Q | I | D | V | A | I | K | V | L | K | Q | G | T | E | K | A | D | T | E | E | M | M | R | E | A | Q | I | M | H | Q | L | D | N | P | Y | I | V | R | L | I | G | V | C | Q | A | E | A | L | M | L |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   | . | . | . | . |   |
|   |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   | . | . | . | . | . |   |   |
| Template Sequence |   |
F | D | E | R | P | I | S | V | G | G | N | K | G | E | G | G | F | G | V | V | Y | K | G | Y | V | . |
. |
. |
. |
N | N | T | T | V | A | V | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | E | I | K | V | M | A | K | C | Q | H | E | N | L | V | E | L | L | G | F | S | . |
. |
. |
. |
. |
C | L |
| Template Known Secondary structure |   |
T |
|
| S |
| G | G | G | T | S |
|
|
|  |  | T | T |  |  |
|  |  |  |  |  | . | . | . | . | T | T |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |
| . | . | . | . | . |
|  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . |
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
. | . | . | . | . | 210 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | |
|
|
|
|
. | . |
|   |
|   |   |
413 | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | |
|
430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | M | E | M | A | G | G | G | P | L | H | K | F | L | V | G | K | . |
. |
R | E | E | I | P | V | S | N | V | A | E | L | L | H | Q | V | S | M | G | M | K | Y | L | E | E | K | N | F | V | H | R | D | L | A | A | R | N | V | L | L | V | N | R | H | Y | A | K | I | S | D | F | G | L | S | K | A | L | G | A | D | D |
| Query Conservation |   |
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
V | Y | V | Y | M | P | N | G | S | L | L | D | R | L | S | C | L | D | G | T | P | P | L | S | W | H | M | R | C | K | I | A | Q | G | A | A | N | G | I | N | F | L | H | E | N | H | H | I | H | R | D | I | K | S | A | N | I | L | L | D | E | A | F | T | A | K | I | S | D | F | G | L | A | R | A | S | E | V | M | R |
| Template Known Secondary structure |   |
 |  |  |
|
| T | T |
| B |  |  |  |  |  | T | T | G | G | G |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| S | S |
|  |  |
|
|
|
|
|
| Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 |
|   |
|   |   |
491 | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 550 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | Y | Y | T | A | R | S | A | G | K | W | P | L | K | W | Y | A | P | E | C | I | N | F | R | K | F | S | S | R | S | D | V | W | S | Y | G | V | T | M | W | E | A | L | S | Y | G | Q | K | P | Y | K | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | K | G | P | E | V | M | A | F | I | E | Q | G | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
I | V | G | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
A | Y | M | A | P | E | A | L | R | G | E | I | T | P | K | S | D | I | Y | S | F | G | V | V | L | L | E | I | I | T | . |
G | L | P | A | V | D | E | H | R | E | P | Q | L | L | L | D | I | K | E | E | I | E | D | E | E | K | T | I | E | D | Y | I | D | K | K |
| Template Known Secondary structure |   |
|
| S |
| G | . | . | . | . | . | . | . | . | . | G | G |
|
| T | T | T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
| S | B |
| T | T | S | S | S | S | B | G | G | G |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  | S |
| S | S |
| Template Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
348 | . | 350 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | |
. | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . |
|   |
|   |   |
557 | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | M | E | C | P | P | E | C | P | P | E | L | Y | A | L | M | S | D | C | W | I | Y | K | W | E | D | R | P | D | F | L | T | V | E | Q | R | M | R | A | C |
| Query Conservation |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|
| Template Sequence |   |
M | N | D | A | D | S | T | S | V | E | A | M | Y | S | V | A | S | Q | C | L | H | E | K | K | N | K | R | P | D | I | K | K | V | Q | Q | L | L | Q | E | M |
| Template Known Secondary structure |   |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | T | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
418 | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . |
|   |