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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank7Aligned Residues366
% Identity36%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  ERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPR. KEQGTYALSLI. . . . . YGKTVYHYLISQDKAGKYCIPEGTKFDTL
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Template Sequence  ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTL
Template Known Secondary structure  GGSTTTT

TSTT

TT

SSSTT
TTTB

STT
SSTTSSS
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   119120.........130.........140.........150.........160.........170.........180.........190........
 
   233......240.........250.........260.........270.........280.........290.........300.........310..
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Query Sequence  WQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDT
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Template Sequence  QELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTSS
SS
SS


SB










TT
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   199200.........210.........220.........230...
 
   313......320.........330.........340.........350.........360.........370.........380.........390..
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Query Sequence  SVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQ
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Template Sequence  . . . . . . . . . . . . . . . . . . WEIPRESLKLEKKLGAGQFGEVWMATYNKH. . . TKVAVKTMKPGS. . MSVEAFLAEANVMKT
Template Known Secondary structure  ..................SB

GGGTTTTT...


S..S
T
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   234.....240.........250.........260... ......270..... ....280.........290
 
   393......400.........410.........420......... 430.........440.........450.........460.........470.
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Query Sequence  LDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGK. REEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVN
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Template Sequence  LQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSA
Template Known Secondary structure 


TTB


SSS


TT
BSTTGGG

TT


S

SGGG
T
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   291........300.........310.........320.........330.........340.........350.........360.........370
 
   472.......480.........490.........500.........510.........520.........530.........540.........550.
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Query Sequence  RHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAF
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Template Sequence  SLVCKIADFGLAR. . . . . . . . . . . . . . . VIPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRA
Template Known Secondary structure  T



TTGGG...............T

GGGS




TTT

SSTT

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   371........380... ......390.........400.........410.........420.........430.....
 
   552.......560.........570.........580.........590.........600.......
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Query Sequence  IEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGP
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Template Sequence  LERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQEEIP
Template Known Secondary structure  TT





TT

T
SSGGGS

TTTS
GGG




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   449450.........460.........470.........480.........490.........500....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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