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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank4Aligned Residues380
% Identity39%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   159160.........170.........180.........190.. .......200... ......210.........220.........230..
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Query Sequence  ERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPR. KEQGTYALSLI. . . . . YGKTVYHYLISQDKAGKYCIPEGTKFDTL
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Template Sequence  QAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSL
Template Known Secondary structure  GGSTTS

T
TT

TT

SSSTT
TTT
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   144.....150.........160.........170.........180.........190.........200.........210.........220...
 
   233......240.........250.........260.........270.........280.........290.........300.........310..
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Query Sequence  WQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDT
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Template Sequence  QQLVAYYSKHADGLCHRLTTVCPTSKP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 

TTSSS



B





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   224.....230.........240.........250
 
   313......320.........330.........340.........350.........360.........370.........380.........390..
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Query Sequence  SVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQ
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Template Sequence  . . . . . . . . . QTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT. . . TRVAIKTLKPGT. . MSPEAFLQEAQVMKK
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TTB

GGGTTTTT...
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   251........260.........270.........280......... 290.........300. ........310......
 
   393......400.........410.........420.........430.. .......440.........450.........460.........470.
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Query Sequence  LDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREE. IPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVN
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Template Sequence  LRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGE
Template Known Secondary structure 


TTB


SSS


TTS

TT
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SGGG
G
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   317..320.........330.........340.........350.........360.........370.........380.........390......
 
   472.......480.........490.........500.........510.........520.........530.........540.........550.
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Query Sequence  RHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAF
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Template Sequence  NLVCKVADFGLARLIEDNE. . YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQ
Template Known Secondary structure  GG



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   397..400.........410..... ....420.........430.........440.........450.........460.........470....
 
   552.......560.........570.........580.........590.........600.......
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Query Sequence  IEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGP
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Template Sequence  VERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPG
Template Known Secondary structure  TT





TT

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SSGGGS

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   475....480.........490.........500.........510.........520.........530
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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