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Job DescriptionP43403
Confidence100.00%DateThu Apr 26 09:45:10 BST 2012
Rank6Aligned Residues365
% Identity38%Templatec1k9aB_
PDB info PDB header:transferaseChain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60.........70.........80
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Query Sequence  MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGP
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Template Sequence  AGTKLSLMPWFHGKITREQAERLLYPP. . ETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYH. ASKLSIDEEVYFENL
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SSSS
TTB

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TT.TTSSSSS
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   73......80.........90......... 100.........110.........120.........130.... .....140.........
 
   81........90.........100.........110.........120.........130.........140.........150.........160
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Query Sequence  AELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHER
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Template Sequence  MQLVEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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TTSSS


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   150.........160.........170.........180.....
 
   161........170.........180.........190.........200.........210.........220.........230.........240
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Query Sequence  MPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   241........250.........260.........270.........280.........290.........300.........310.........320
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Query Sequence  LKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYS
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   321........330.........340.........350.........360.........370.........380.........390.........400
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Query Sequence  DPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVR
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Template Sequence  . . . . . . . . SGWALNMKELKLLQTIGKGEFGDVMLGDYR. . . . GNKVAVKCIKNDATAQ. . . AFLAEASVMTQLRHSNLVQ
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B

GGG

TTT....TSS
TTS...TT


TTB

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   186...190.........200.........210..... ....220.........230. ........240.........250
 
   401.... ....410.........420........ .430.........440.........450.........460.........470.......
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Query Sequence  LIGVC. . QAEALMLVMEMAGGGPLHKFLVG. KREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKI
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Template Sequence  LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKV
Template Known Secondary structure 
SSS



TT
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TTT

TT
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GGG
TT

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   251........260.........270.........280.........290.........300.........310.........320.........330
 
   478.480.........490.........500.........510.........520.........530.........540.........550.......
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Query Sequence  SDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKR
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Template Sequence  SDFGLTK. . . . . . . . . . . . EAGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYK
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TT
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TTTS
TTT


TTT

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TTTTTT

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   331...... ..340.........350.........360.........370.........380.........390........
 
   558.560.........570.........580.........590.........
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Query Sequence  MECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYS
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Template Sequence  MDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRTH
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TT

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   405....410.........420.........430.........440......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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