Job Description P43403 Confidence 100.00% Date Thu Apr 26 09:45:10 BST 2012 Rank 44 Aligned Residues 219 % Identity 57% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	A	A	H	L	P	F	F	Y	G	S	I	S	R	A	E	A	E	E	H	L	K	L	A	G	M	A	D	G	L	F	L	L	R	Q	C	L	R	S	L	G	G	Y	V	L	S	L	V	H	D	V	R	F	H	H	F	P	I	E	R	Q	L	N	G	T	Y	A	I	A	G	G	K	A	H	C	G	P	A	E	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	A	N	H	L	P	F	F	F	G	N	I	T	R	E	E	A	E	D	Y	L	V	Q	G	G	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L
Template Known Secondary structure			G	G	G		T	T			S	S												T	T	T			T	T								S	S	S	T	T									S	S	S										T	T	T					T	T	S			B	S	S
Template Predicted Secondary structure
Template SS confidence
		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	E	F	Y	S	R	D	P	D	G	L	P	C	N	L	R	K	P	C	N	R	P	S	G	L	E	P	Q	P	G	V	F	D	C	L	R	D	A	M	V	R	D	Y	V	R	Q	T	W	K	L	E	G	E	A	L	E	Q	A	I	I	S	Q	A	P	Q	V	E	K	L	I	A	T	T	A	H	E	R	M	P	W
Query Conservation
Alig confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	W
Template Known Secondary structure						T	T			T	T	S	S	S				S	B					T	T					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.											T	S	G	G	G		T	T
Template Predicted Secondary structure																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		89	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.																																			.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	H	S	S	L	T	R	E	E	A	E	R	K	L	Y	S	G	A	Q	T	D	G	K	F	L	L	R	P	R	K	E	Q	G	T	Y	A	L	S	L	I	Y	G	K	T	V	Y	H	Y	L	I	S	Q	D	K	A	G	K	Y	C	I	P	E	G	T	K	F	D	T	L	W	Q	L	V	E	Y	L	K	L	K	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A
Template Known Secondary structure																	S	S				T	T								S	S	S	S									T	T											T	T	S					T	T	S			B	S										T	T
Template Predicted Secondary structure
Template SS confidence
		169	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
		244	.	.	.	.	.	250	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	G	L	I	Y	C	L	K	E	A	C	P	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	G	L	L	R	V	L	T	V	P	C	Q	K
Template Known Secondary structure		T	T	S	S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		249	250	.	.	.	.	.	.	.	.	.	260	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions