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Job DescriptionQ6XZF7
Confidence100.00%DateThu Apr 26 09:30:42 BST 2012
Rank1Aligned Residues258
% Identity39%Templatec2dx1A_
PDB info PDB header:signaling proteinChain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef
Resolution2.36 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   245....250.........260.........270.........280.........290.........300.........310.........320....
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Query Sequence  GTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVEETMALPQEGSLARIPETS
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Template Sequence  VVCAEALWDHVTXDDQELGFKAGDVIEVXDATNREWWWGRVADGEGWFPASFVRLRVNQDA. . . . . . . . . . . . . . . . . . .
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SS
B



TTB

B
TT


SSS
SS
GGG
S



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   125....130.........140.........150.........160.........170.........180.....
 
   325....330.........340.........350.........360.........370.........380.........390.........400....
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Query Sequence  LDCLENTLGVEEQRHETSDHEAEEPDCIISEAPTSPLGHLTSEYDTDRNSYQDEDTAGGPPRSPGVEWEMPLATDSPTSD
Query Conservation                                                          
                       
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   405....410.........420.........430.........440.........450.........460.........470.........480....
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Query Sequence  PTEVVNGISSQPQVPFHPNLQKSQYYSTVGGSHPHSEQYPDLLPLEARTRDYASLPPKRMYSQLKTLQKPVLPLYRGSSV
Query Conservation                
                                                                 
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   485....490.........500.........510.........520.........530.........540.........550.........560....
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Query Sequence  SASRVVKPRQSSPQLHNLASYTKKHHTSSVYSISERLEMKPGPQAQGLVMEAATHSQGDGSTDLDSKLTQQLIEFEKSLA
Query Conservation         
                       
                                                
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   565....570.........580.........590.........600.........610.........620.........630.........640....
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Query Sequence  GPGTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQELPERRKALRPPPPRPCTPVSTSPHLLVDQNLKPAPPLVVRPSRP
Query Conservation                                                                                  
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   645....650.........660.........670.........680.........690.........700.........710.........720....
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Query Sequence  APLPPSAQQRTNAVSPKLLSRHRPTCETLEKEGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLEEKQD
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   725....730.........740.........750.........760.........770.........780.........790.........800....
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Query Sequence  ESSRAETLEDLKFCESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAENPEQRMLEKRAKVIEELLQTERDYIRDLE
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QSSKDQXRTNVINEILSTERDYIKHLR
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   207..210.........220.........230...
 
   805....810........ .820.........830.........840........ .850.........860.........870....
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Query Sequence  MCIERIMVPMQQAQ. . VPNIDFEGLFGNMQMVIKVSKQLLAALEIS. . . . . . . . DAVGPVFLGHRDELEGTYKIYCQNHD
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Template Sequence  DICEGYVRQCRKRADXFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQ. IYSEYCNNHP
Template Known Secondary structure  TTT
TTT

TTTT

SSSGGG


T.T
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   234.....240.........250.........260.........270.........280.........290.........300.. .......310..
 
   875....880.........890.........900.........910.........920.........930.........940.........950....
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Query Sequence  EAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTNAV
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Template Sequence  NACVELSRLTKLSKYVYFFEACRLLQK. . . . . . . . XIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAAL
Template Known Secondary structure  T
T........

S

TS
TT
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   313......320.........330......... 340.........350.........360.........370.........380....
 
   955....960.........970.........980...
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Query Sequence  LAVKEINVNINEYKRRKDLVLKYRKGDED
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Template Conservation       
   


  
  
    
  
   
Template Sequence  HAXKNVAQLINERKRRLENIDKIAQWQSS
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   385....390.........400.........410...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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