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Job DescriptionP08100
Confidence100.00%DateWed Jun 6 09:21:49 BST 2012
Rank5Aligned Residues282
% Identity26%Templatec3uonA_
PDB info PDB header:signaling protein/antagonistChain: A: PDB Molecule:human m2 muscarinic acetylcholine, receptor t4 lysozyme PDBTitle: structure of the human m2 muscarinic acetylcholine receptor bound to2 an antagonist
Resolution3.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   35....40.........50.........60.........70.........80.........90.........100.........110....
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Query Sequence  WQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEG
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Template Sequence  FEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWL
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GGG
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   21........30.........40.........50.........60.........70.........80.........90.........100
 
   115....120.........130.........140........ .150.........160.........170.........180.........190...
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Query Sequence  FFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF. GENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYT
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Template Sequence  ALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
Template Known Secondary structure 
TTTSGGG

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   101........110.........120.........130.........140.........150.........160.........170.........180
 
   194.....200.........210.........220.........230....
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Query Sequence  LKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  FSNA. . . . AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLN
Template Known Secondary structure  GGS....TTT


S


TTS
TT



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   181... .....190.........200.........210.........220.........230.........240.........250......
 
  
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Template Sequence  AAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRM
Template Known Secondary structure  SS

TTB

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TTTS
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   1041........1050.........1060.........1070.........1080.........1090.........1100.........1110.........1120
 
   235....240.........250.........260.........270.........280
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQG
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Template Sequence  LQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAP
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TTSSSSSTTS


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ST
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   1121........1130.........1140.........1150.........1160.........1170.........1180.........1190.........1200
 
   281........290.........300.........310.........320.
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Query Sequence  SNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTI
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Template Sequence  C. IPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL
Template Known Secondary structure  T.S
TTT

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   416 ...420.........430.........440.........450.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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