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Job DescriptionP42680
Confidence100.00%DateFri May 25 09:36:11 BST 2012
Rank97Aligned Residues333
% Identity21%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
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Query Sequence  NFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGRAEKKYRKGFIDVSKIKCVEIVKNDDGVIPCQNKYPFQ
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Template Sequence  DVAIVKEGWLHKRGEY. . . . . IKTWRPRYFLLKNDGTFIGYKERPQD. VEAPLNNFSVAQCQLMKTE. . . . . RPRPNTFI
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SS.....S

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GGGB
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   3......10........ .20.........30.........40.... .....50.........60... ......70.
 
   82... ....90.........100.........110.........120.........130.........140.........150.........160
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Query Sequence  VVHD. ANTLYIFAPSPQSRDLWVKKLKEEIKNNNNIMIKYHPKFWTDGSYQCCRQTEKLAPGCEKYNLFESSIRKALPPA
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Template Sequence  IRCLQWTTVIERTFTPEEREEWTTAIQTVADGLKKQVTM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT

TTGGGTT


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   75....80.........90.........100.........110...
 
   161........170.........180.........190.........200.........210.........220.........230.........240
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Query Sequence  PETKKRRPPPPIPLEEEDNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSN
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   241........250.........260.........270.........280.........290.........300.........310.........320
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Query Sequence  NLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKKYYLAEKHAF
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   321........330.........340.........350.........360.........370.........380.........390. ........
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Query Sequence  GSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWRA. QYKVAIKA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
Template Known Secondary structure  ...............................................TSTTTTT

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   148.150.........160.........170.........180
 
   400.........410.........420.........430.........440.........450.........460.........470.........
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Query Sequence  IREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEY
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Template Sequence  LK. . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER. VFSEDRARFYGAEIVSALDY
Template Known Secondary structure  ......GGGS



GGGTS

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   181. .......190.........200.........210.........220.........230... ......240.........250...
 
   480.. .......490.........500.........510.........520.........530.........540.........550........
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Query Sequence  LER. NSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEV
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Template Sequence  LHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEPE. . . . . . . . . . . . . . . YLAPEVLEDNDYGRAVDWWGLGVVMYEM
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GGG
TTS




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   264.....270.........280.........290.........300 .........310.........320........
 
   559560.........570.........580.........590.........600......... 610.......
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Query Sequence  FTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGR. . . . . PSFEDLLR
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Template Sequence  MC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  .SS
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   343. .....350.........360..... ....370.........380.........390.........400....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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