Return to main results Retrieve Phyre Job Id

Job DescriptionP42680
Confidence100.00%DateFri May 25 09:36:11 BST 2012
Rank80Aligned Residues242
% Identity62%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   360.........370.........380.........390.........400.........410.........420.........430.........
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Query Sequence  YEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIY
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKE. . . . . . . FIEEAKVMMNLSHEKLVQLYGVCTKQRPIF
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GGGB

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TT


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   392.......400.........410.........420.........430.... .....440.........450.........460....
 
   440.........450.........460.........470.........480.........490.........500.........510.........
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Query Sequence  IVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQY
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Template Sequence  IITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . .
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   472.......480.........490.........500.........510.........520.........530.........540...
 
   520.........530.........540.........550.........560.........570.........580.........590.........
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Query Sequence  TSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVML
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Template Sequence  . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
Template Known Secondary structure  .........GGG





TTS

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   561........570.........580.........590.........600.........610.........620.........630.
 
   600.........610.........620.....
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Query Sequence  RCWQEKPEGRPSFEDLLRTIDELVEC
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Template Sequence  SCWHEKADERPTFKILLSNILDVMDE
Template Known Secondary structure  TT
SSGGGS

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   632.......640.........650.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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