Return to main results Retrieve Phyre Job Id

Job DescriptionP42680
Confidence100.00%DateFri May 25 09:36:11 BST 2012
Rank206Aligned Residues247
% Identity36%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   361........ 370.........380.........390... ......400....... ..410.........420.........430..
Predicted Secondary structure 


..






....





..







Query SS confidence 








. .























. . . .













. .
























Query Sequence  EKWEINPSE. . LTFMRELGSGLFGVVRLGKWRAQY. . . . KVAIKAIREGAMCE. . EDFIEEAKVMMKLTHPKLVQLYGVC
Query Conservation     

    ..      

 
 

 
  
      .... 



 

      ..  
  
   
  
 
 


 
 
  
Alig confidence 








..























....













..
























Template Conservation      
            

 
 

 

             



 
              
   
  
 




      
Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC
Template Known Secondary structure  TTTB

STT

SSSTTT

S
S
STTSTT


TTB



Template Predicted Secondary structure 



























Template SS confidence 















































































   1067..1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140......
 
   433..... .440.........450.........460.........470.........480.........490.........500.........510.
Predicted Secondary structure 

.





























Query SS confidence 





.








































































Query Sequence  TQQKPI. YIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMA
Query Conservation        . 

 
    


   
      
       
  


 

 


   






  



     


 




Alig confidence 





.








































































Template Conservation                                           
                                 
    
Template Sequence  LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADFLPV
Template Known Secondary structure 


SS



TT
B
TT


BTT


S


GGG
TT






G
Template Predicted Secondary structure 



























































Template SS confidence 















































































   1147..1150.........1160.........1170.........1180.........1190.........1200.........1210.........1220......
 
   512.......520.........530.........540.........550.........560.........570.........580.........590.
Predicted Secondary structure 







































Query SS confidence 















































































Query Sequence  RYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLAS
Query Conservation 
                    


       
 





 

 
 

 
 
  
            
  
     
    
Alig confidence 
..................




























































Template Conservation   ..................                
  
 

   

 
   
             
             
Template Sequence  K. . . . . . . . . . . . . . . . . . WMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCP
Template Known Secondary structure  G..................GS




TTS

S
TTS
SS
TT





TT

Template Predicted Secondary structure 
..................






































Template SS confidence 















































































   1248 .1250.........1260.........1270.........1280.........1290.........1300.........
 
   592.......600.........610.........620.....
Predicted Secondary structure 






Query SS confidence 

































Query Sequence  NYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVEC
Query Conservation    
  

  
   

  


   
   
  
   
Alig confidence 

































Template Conservation    
  

  

  

  


  


  
  
   
Template Sequence  DPLYEVMLKCWHPKAEMRPSFSELVSRISAIFST
Template Known Secondary structure  T
SSGGGS

T
Template Predicted Secondary structure 






Template SS confidence 

































   1310.........1320.........1330.........1340...
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions