|   |   |
369 | 370 | . | . | . | . | . | . | . | . | . | |
|
380 | . | . | . | . | . | . | . | . | . | 390 | |
. | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | |
|
|
. | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | L | T | F | M | R | E | L | G | S | G | . |
. |
L | F | G | V | V | R | L | G | K | W | R | . |
A | Q | Y | K | V | A | I | K | A | I | R | E | G | A | M | C | E | E | . |
. |
. |
D | F | I | E | E | A | K | V | M | M | K | L | T | H | P | K | L | V | Q | L | Y | G | V | C | T | Q | Q | K | P | I | Y | I | V | T |
| Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |
| . | . |   |
|
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   | . | . | . |   |
|   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
| Template Sequence |   |
C | Y | E | L | L | T | V | I | G | K | G | F | E | D | L | M | T | V | N | L | A | R | Y | K | P | T | G | E | Y | V | T | V | R | R | I | N | L | E | A | C | S | N | E | M | V | T | F | L | Q | G | E | L | H | V | S | K | L | F | N | H | P | N | I | V | P | Y | R | A | T | F | I | A | D | N | E | L | W | V | V | T |
| Template Known Secondary structure |   |
G |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
|   |
|   |   |
443 | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | F | M | E | R | G | C | L | L | N | F | L | R | Q | R | Q | G | . |
H | F | S | R | D | V | L | L | S | M | C | Q | D | V | C | E | G | M | E | Y | L | E | R | N | S | F | I | H | R | D | L | A | A | R | N | C | L | V | S | E | A | G | V | V | K | V | S | D | F | G | M | A | R | Y | V | L | D | D | Q | Y | T | S |
| Query Conservation |   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   | . |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
S | F | M | A | Y | G | S | A | K | D | L | I | C | T | H | F | M | D | G | M | N | E | L | A | I | A | Y | I | L | Q | G | V | L | K | A | L | D | Y | I | H | H | M | G | Y | V | H | R | S | V | K | A | S | H | I | L | I | S | V | D | G | K | V | Y | L | S | G | L | R | S | N | L | S | M | I | S | H | G | Q | R | Q |
| Template Known Secondary structure |   |
 |
|
| T | T |  |  |  |  |  |  |  |  |  | T |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
| G | G | G |
|  |  |
|  |  | T | T |  |  |
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
|   |
|   |   |
522 | . | . | |
|
|
|
|
|
. | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | |
|
. | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . |
| Predicted Secondary structure |   |
 |
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | S | G | . |
. |
. |
. |
. |
. |
A | K | F | P | V | K | W | C | P | P | E | V | F | N | Y | S | . |
. |
R | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | V | F | T | E | G | R | M | P | F | E | K | Y | T | N | Y | E | V | V | T | M | V | T | R | G | H | R | L | Y | Q | P | K | L | A | S | N | Y |
| Query Conservation |   |
  |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   | . | . |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
| Template Sequence |   |
R | V | V | H | D | F | P | K | Y | S | V | K | V | L | P | W | L | S | P | E | V | L | Q | Q | N | L | Q | G | Y | D | A | K | S | D | I | Y | S | V | G | I | T | A | C | E | L | A | N | . |
G | H | V | P | F | D | M | P | A | T | Q | M | L | L | E | K | L | . |
. |
. |
. |
. |
. |
. |
V | P | C | L | F | S | P | H |
| Template Known Secondary structure |   |
S |
| B |
|
|
|
| S | S |
| G | G | G | G | G | G | S |
|  |  |  |  | S |
|
| T | T |
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
|
|
|
|
|
|  |  |  |  |  |  | T | T |
| . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |
| Template Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . |
|   |
|   |   |
594 | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | Y | E | V | M | L | R | C | W | Q | E | K | P | E | G | R | P | S | F | E | D | L | L | R |
| Query Conservation |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
F | H | H | F | V | E | Q | C | L | Q | R | N | P | D | A | R | P | S | A | S | T | L | L | N |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
|   |