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Job DescriptionP42680
Confidence100.00%DateFri May 25 09:36:11 BST 2012
Rank112Aligned Residues239
% Identity24%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   366...370.........380.........390 .........400. ........410.........420.........430.........440
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Query Sequence  NPSELTFMRELGSGLFGVVRLGKWR. AQYKVAIKAIR. . . . EGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYI
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYF
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
   441........450.........460.........470.........480.........490.........500.........510.........520
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Query Sequence  VTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYT
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Template Sequence  GLSYAKNGELLKYIRKIG. SFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . .
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   158.160.........170..... ....180.........190.........200.........210.........220.........230
 
   521........530.........540.........550.........560.........570.........580.........590.........600
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Query Sequence  SSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLR
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Template Sequence  . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVEK
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   242.......250.........260.........270....... ..280.........290........ .300.........310.....
 
   601........610.......
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Query Sequence  CWQEKPEGRPSFEDLLR
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Template Sequence  LLVLDATKRLGCEEMEG
Template Known Secondary structure  TS
SSTTSSTTSGGGTT
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   316...320.........330..
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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