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Job DescriptionP42680
Confidence100.00%DateFri May 25 09:36:11 BST 2012
Rank69Aligned Residues250
% Identity24%Templatec2j51A_
PDB info PDB header:transferaseChain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
Resolution2.1 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   366...370.........380.........390 .........400....... ..410.........420.........430.........440...
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Query Sequence  NPSELTFMRELGSGLFGVVRLGKWR. AQYKVAIKAIREGAMCE. EDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTE
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Template Sequence  PEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIE
Template Known Secondary structure  GGGTTTTTT


SSSTT


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TT
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   30.........40.........50.........60.........70.........80.........90.........100.........
 
   444.....450.........460.........470.........480.........490.........500.........510.........520...
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Query Sequence  FMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSS
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Template Sequence  FCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA. KNTRTIQRRD
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   110.........120.........130.........140.........150.........160.........170........ .180........
 
   524.....530....... ..540.........550.........560.........570.........580.. .......590......
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Query Sequence  GAKFPVKWCPPEVF. . . . . NYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGH. . RLYQPKLASNYVYE
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Template Sequence  SFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE. IEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKD
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   189190.........200.........210.........220.........230 .........240.........250.........260.......
 
   597..600.........610.......
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Query Sequence  VMLRCWQEKPEGRPSFEDLLR
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Template Sequence  FLKKCLEKNVDARWTTSQLLQ
Template Known Secondary structure  S
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   268.270.........280........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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