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Job DescriptionP42680
Confidence100.00%DateFri May 25 09:36:11 BST 2012
Rank18Aligned Residues263
% Identity36%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   361........370.........380.........390 .........400....... ..410.........420.........430..
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Query Sequence  EKWEINPSELTFMRELGSGLFGVVRLGKWR. . . . . . AQYKVAIKAIREGAMCE. . EDFIEEAKVMMKLTHPKLVQLYGVC
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Template Sequence  PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGAC
Template Known Secondary structure  TTTB

GGG
SSSTGGG
SS

TT

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TTB

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   715....720.........730.........740.........750.........760.........770.........780.........790....
 
   433......440.........450........ .460.........470.........480.........490.........500.....
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Query Sequence  TQQKPIYIVTEFMERGCLLNFLRQRQ. . . . . . . GHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKV
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Template Sequence  SQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKI
Template Known Secondary structure 
SSSS


TT
BTTTSTT


TT



SGGGTTT
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   795....800.........810.........820.........830.........840.........850.........860.........870....
 
   506...510... ......520.........530.........540.........550.........560.........570.........580....
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Query Sequence  SDFGMARY. VLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRL
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Template Sequence  SDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRM
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TT

TTTS

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   891........900.........910.........920.........930.........940.........950.........960.........970
 
   585....590.........600.........610.........620...
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Query Sequence  YQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELV
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Template Sequence  ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM
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TT

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   971........980.........990.........1000.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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