Job Description P42680 Confidence 100.00% Date Fri May 25 09:36:11 BST 2012 Rank 6 Aligned Residues 422 % Identity 38% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å

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		183	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.		.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
Predicted Secondary structure																																									.
Query SS confidence																																									.
Query Sequence		I	V	V	A	M	Y	D	F	Q	A	A	E	G	H	D	L	R	L	E	R	G	Q	E	Y	L	I	L	E	K	N	D	V	H	W	W	R	A	R	D	.	K	Y	G	N	E	G	Y	I	P	S	N	Y	V	T	G	K	K	S	N	N	L	D	Q	Y	E	W	Y	C	R	N	M	N	R	S	K	A	E	Q	L	L
Query Conservation																																									.
Alig confidence																															.										.															.	.
Template Conservation																															.																									.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	.	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	.	.	R	V	D	S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T									.		T	T							T	T	T								G	G	G			.	.		T	T	S	G	G	G	S	T	T			T	T
Template Predicted Secondary structure																															.																									.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.			.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.
		262	.	.	.		.	.	.	.	270	.	.	.	.	.		.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.
Predicted Secondary structure						.											.
Query SS confidence						.											.
Query Sequence		R	S	E	D	.	K	E	G	G	F	M	V	R	D	S	.	S	Q	P	G	L	Y	T	V	S	L	Y	T	K	F	G	G	E	G	S	S	G	F	R	H	Y	H	I	K	E	T	T	T	S	P	K	K	Y	Y	L	A	E	K	H	A	F	G	S	I	P	E	I	I	E	Y	H	K	H	N	A	A	G	L	V	T
Query Conservation						.											.
Alig confidence						.											.														.																					.	.
Template Conservation																															.																					.	.
Template Sequence		L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	.	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	.	.	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q
Template Known Secondary structure		T	S	T	T			T	T								S	S	S	T	T										.		T	T	T										B			S	T	T		.	.			S	S	T	T	S			S	S								T	T	S	S		S	S		S	S
Template Predicted Secondary structure																															.																					.	.
Template SS confidence
		138	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.		.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.			.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.
		340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	R	Y	P	V	S	V	K	G	K	N	A	P	T	T	A	G	F	S	Y	E	K	W	E	I	N	P	S	E	L	T	F	M	R	E	L	G	S	G	L	F	G	V	V	R	L	G	K	W	R	A	Q	Y	K	V	A	I	K	A	I	R	E	G	A	M	C	E	E	D	F	I	E	E	A	K	V	M	M	K
Query Conservation
Alig confidence																.	.	.	.
Template Conservation																.	.	.	.
Template Sequence		K	L	S	V	P	C	M	S	S	K	P	Q	K	P	.	.	.	.	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T
Template Known Secondary structure					S	B										.	.	.	.			T	T		S	B			G	G	G											T	T									T	T	T												S	S														T
Template Predicted Secondary structure																.	.	.	.
Template SS confidence
		215	.	.	.	.	220	.	.	.	.	.	.	.	.					.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
		420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.		460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.
Query SS confidence																																										.
Query Sequence		L	T	H	P	K	L	V	Q	L	Y	G	V	C	T	Q	Q	K	P	I	Y	I	V	T	E	F	M	E	R	G	C	L	L	N	F	L	R	Q	R	Q	G	.	H	F	S	R	D	V	L	L	S	M	C	Q	D	V	C	E	G	M	E	Y	L	E	R	N	S	F	I	H	R	D	L	A	A	R	N	C	L	V	S
Query Conservation																																										.
Alig confidence															.																											.
Template Conservation															.
Template Sequence		L	Q	H	D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S
Template Known Secondary structure					T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S			S	G	G	G
Template Predicted Secondary structure															.
Template SS confidence
		291	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.
		499	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	A	G	V	V	K	V	S	D	F	G	M	A	R	Y	V	L	D	D	Q	Y	T	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V	F	N	Y	S	R	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	T	E	G	R	M	P	F	E	K	Y	T	N	Y	E	V	V	T	M	V
Query Conservation
Alig confidence																.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L
Template Known Secondary structure		T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S																												T	T	T			S	S	T	T
Template Predicted Secondary structure																.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.
		579	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	R	G	H	R	L	Y	Q	P	K	L	A	S	N	Y	V	Y	E	V	M	L	R	C	W	Q	E	K	P	E	G	R	P	S	F	E	D	L	L	R	T	I	D	E	L	V	E	C	E	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S
Template Known Secondary structure			T	T							T	T													T		S	S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.