Job Description P42680 Confidence 100.00% Date Fri May 25 09:36:11 BST 2012 Rank 5 Aligned Residues 428 % Identity 40% Template c1k9aB_ PDB info PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution Resolution 2.50 Å

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		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210		.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.					.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
Predicted Secondary structure																																		.																											.	.	.	.
Query SS confidence																																		.																											.	.	.	.
Query Sequence		N	S	E	E	I	V	V	A	M	Y	D	F	Q	A	A	E	G	H	D	L	R	L	E	R	G	Q	E	Y	L	I	L	E	.	K	N	D	V	H	W	W	R	A	R	D	K	Y	G	N	E	G	Y	I	P	S	N	Y	V	T	G	.	.	.	.	K	K	S	N	N	L	D	Q	Y	E	W	Y	C	R	N	M	N
Query Conservation																																		.																											.	.	.	.
Alig confidence																																		.																											.	.	.	.
Template Conservation
Template Sequence		P	S	G	T	E	C	I	A	K	Y	N	F	H	G	T	A	E	Q	D	L	P	F	C	K	G	D	V	L	T	I	V	A	V	T	K	D	P	N	W	Y	K	A	K	N	K	V	G	R	E	G	I	I	P	A	N	Y	V	Q	K	R	E	G	V	K	A	G	T	K	L	S	L	M	P	W	F	H	G	K	I	T
Template Known Secondary structure			T	T						S	S		B			S	S	T	T	B			B		T	T										S	S	T	T							T	T	S							G	G	G										S	S	S			S		T	T	B			S
Template Predicted Secondary structure
Template SS confidence
		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
		254	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.		.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.
Predicted Secondary structure																								.
Query SS confidence																								.
Query Sequence		R	S	K	A	E	Q	L	L	R	S	E	D	K	E	G	G	F	M	V	R	D	S	.	S	Q	P	G	L	Y	T	V	S	L	Y	T	K	F	G	G	E	G	S	S	G	F	R	H	Y	H	I	K	E	T	T	T	S	P	K	K	Y	Y	L	A	E	K	H	A	F	G	S	I	P	E	I	I	E	Y	H	K	H
Query Conservation																								.
Alig confidence												.												.													.	.	.	.	.	.																.	.	.
Template Conservation												.																									.	.	.	.	.	.																.	.	.
Template Sequence		R	E	Q	A	E	R	L	L	Y	P	.	P	E	T	G	L	F	L	V	R	E	S	T	N	Y	P	G	D	Y	T	L	C	V	S	C	.	.	.	.	.	.	E	G	K	V	E	H	Y	R	I	M	Y	H	A	S	K	.	.	.	L	S	I	D	E	E	V	Y	F	E	N	L	M	Q	L	V	E	H	Y	T	T
Template Known Secondary structure									T		S	.			T	T								S	S	S	T	T									.	.	.	.	.	.	T	T											T	T		.	.	.			S	S	S	S	S		B	S	S
Template Predicted Secondary structure												.																									.	.	.	.	.	.																.	.	.
Template SS confidence
		89	90	.	.	.	.	.	.	.	.		.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.							.	.	.	.	.	.	.	130	.	.	.	.	.	.	.				.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
		333	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	A	A	G	L	V	T	R	L	R	Y	P	V	S	V	K	G	K	N	A	P	T	T	A	G	F	S	Y	E	K	W	E	I	N	P	S	E	L	T	F	M	R	E	L	G	S	G	L	F	G	V	V	R	L	G	K	W	R	A	Q	Y	K	V	A	I	K	A	I	R	E	G	A	M	C	E	E	D	F	I	E
Query Conservation
Alig confidence																										.																																		.																	.
Template Conservation																										.																																		.																	.
Template Sequence		D	A	D	G	L	C	T	R	L	I	K	P	K	V	M	E	G	T	V	A	A	Q	D	E	.	F	Y	R	S	G	W	A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	G	N	K	V	A	V	K	C	I	K	N	D	A	T	A	Q	.	A	F	L	A
Template Known Secondary structure				T	T	S	S	S				S	B				S	S								.				T	T		B			G	G	G											T	T									T	.	T									S	S		T	T	S		.
Template Predicted Secondary structure																										.																																		.																	.
Template SS confidence
		159	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.		.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.		.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.		.	.	.	.
		413	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.		.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.		.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Predicted Secondary structure																										.																					.
Query SS confidence																										.																					.
Query Sequence		E	A	K	V	M	M	K	L	T	H	P	K	L	V	Q	L	Y	G	V	C	T	Q	Q	K	.	P	I	Y	I	V	T	E	F	M	E	R	G	C	L	L	N	F	L	R	Q	.	R	Q	G	H	F	S	R	D	V	L	L	S	M	C	Q	D	V	C	E	G	M	E	Y	L	E	R	N	S	F	I	H	R	D	L
Query Conservation																										.																					.
Alig confidence																										.																					.
Template Conservation
Template Sequence		E	A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G	G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L
Template Known Secondary structure							T	T				T	T	B										S	S	S										T	T		B										T	T	T																							T	T		B		S
Template Predicted Secondary structure
Template SS confidence
		236	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
		491	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570
Predicted Secondary structure
Query SS confidence
Query Sequence		A	A	R	N	C	L	V	S	E	A	G	V	V	K	V	S	D	F	G	M	A	R	Y	V	L	D	D	Q	Y	T	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V	F	N	Y	S	R	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	T	E	G	R	M	P	F	E	K	Y	T
Query Conservation
Alig confidence																								.	.	.	.	.	.	.	.	.	.
Template Conservation																								.	.	.	.	.	.	.	.	.	.
Template Sequence		A	A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	.	.	.	.	.	.	.	.	.	.	E	A	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P
Template Known Secondary structure			G	G	G					T	T									T	T		B	.	.	.	.	.	.	.	.	.	.							T	T	T	S						T	T	T																				T	T	T			S	S	T	T	S
Template Predicted Secondary structure																								.	.	.	.	.	.	.	.	.	.
Template SS confidence
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.											.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
		571	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	Y	E	V	V	T	M	V	T	R	G	H	R	L	Y	Q	P	K	L	A	S	N	Y	V	Y	E	V	M	L	R	C	W	Q	E	K	P	E	G	R	P	S	F	E	D	L	L	R	T	I	D	E	L	V	E	C	E	E	T	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	K	D	V	V	P	R	V	E	K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	D	V	M	K	N	C	W	H	L	D	A	A	T	R	P	T	F	L	Q	L	R	E	Q	L	E	H	I	R	T	H	E	L	H	L
Template Known Secondary structure		T	T	T						T	T	T							T	T													T		S	S	G	G	G	S																	T	T	T
Template Predicted Secondary structure
Template SS confidence
		392	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450