Email l.a.kelley@imperial.ac.uk Description P52735 Date Wed Jun 6 09:50:28 BST 2012 Unique Job ID 3adc006cc7b0d8b4

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ky9B_ 100.0 56 PDB header:apoptosis Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: autoinhibited vav1 2 c2vrwB_ 100.0 54 PDB header:signaling protein Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor 3 c3bjiA_ 100.0 54 PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1 4 c3ksyA_ 100.0 20 PDB header:signaling protein Chain: A: PDB Molecule:son of sevenless homolog 1; PDBTitle: crystal structure of the histone domain, dh-ph unit, and2 catalytic unit of the ras activator son of sevenless (sos) 5 c2dx1A_ 100.0 27 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef 6 c3odoA_ 100.0 19 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1; PDBTitle: crystal structure of the dh/ph domains of p115-rhogef 7 c1xdvB_ 100.0 21 PDB header:signaling protein Chain: B: PDB Molecule:son of sevenless protein homolog 1; PDBTitle: experimentally phased structure of human the son of2 sevenless protein at 4.1 ang. 8 c1x86A_ 100.0 18 PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa 9 c1xcgA_ 100.0 21 PDB header:signaling protein activator/signaling pr Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 11; PDBTitle: crystal structure of human rhoa in complex with dh/ph2 fragment of pdzrhogef 10 c2dfkA_ 100.0 24 PDB header:cell cycle Chain: A: PDB Molecule:collybistin ii; PDBTitle: crystal structure of the cdc42-collybistin ii complex 11 c3t06E_ 100.0 20 PDB header:signaling protein Chain: E: PDB Molecule:rho guanine nucleotide exchange factor 11; PDBTitle: crystal structure of the dh/ph fragment of pdzrhogef with n-terminal2 regulatory elements in complex with human rhoa 12 c3odxA_ 100.0 20 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1; PDBTitle: crystal structure of an n-terminally truncated linker-dh/ph domains of2 p115-rhogef 13 c3odwB_ 100.0 22 PDB header:signaling protein Chain: B: PDB Molecule:rho guanine nucleotide exchange factor 1; PDBTitle: crystal structure of the linker-dh/ph domains of p115-rhogef 14 c2rgnB_ 100.0 21 PDB header:signaling protein complex Chain: B: PDB Molecule:rhoa/rac/cdc42 exchange factor; PDBTitle: crystal structure of p63rhogef complex with galpha-q and rhoa 15 c1foeA_ 100.0 19 PDB header:signaling protein, immune system/signali Chain: A: PDB Molecule:t-lymphoma invasion and metastasis inducing PDBTitle: crystal structure of rac1 in complex with the guanine2 nucleotide exchange region of tiam1 16 c3mpxA_ 100.0 16 PDB header:lipid binding protein Chain: A: PDB Molecule:fyve, rhogef and ph domain-containing protein 5; PDBTitle: crystal structure of the dh and ph-1 domains of human fgd5 17 c2z0qA_ 100.0 22 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 3; PDBTitle: crystal structure of dh-ph domain of rhogef3(xpln) 18 c1ki1B_ 100.0 20 PDB header:signaling protein Chain: B: PDB Molecule:intersectin long form; PDBTitle: guanine nucleotide exchange region of intersectin in2 complex with cdc42 19 c1dbhA_ 100.0 20 PDB header:gene regulation Chain: A: PDB Molecule:protein (human sos 1); PDBTitle: dbl and pleckstrin homology domains from hsos1 20 c1lb1C_ 100.0 22 PDB header:signaling protein Chain: C: PDB Molecule:guanine nucleotide exchange factor dbs; PDBTitle: crystal structure of the dbl and pleckstrin homology2 domains of dbs in complex with rhoa 21 c1ntyA_ not modelled 100.0 17 PDB header:signaling protein Chain: A: PDB Molecule:triple functional domain protein; PDBTitle: crystal structure of the first dh/ph domain of trio to 1.7 a 22 d1xcga1 not modelled 100.0 22 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 23 d1txda1 not modelled 100.0 19 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 24 d1dbha1 not modelled 100.0 20 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 25 d1f5xa_ not modelled 100.0 49 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 26 d1ki1b1 not modelled 100.0 25 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 27 d2dfka1 not modelled 100.0 27 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 28 c2d86A_ not modelled 100.0 71 PDB header:signaling protein, protein binding Chain: A: PDB Molecule:vav-3 protein; PDBTitle: solution structure of the ch domain from human vav-3 protein 29 c3eo2A_ not modelled 100.0 27 PDB header:splicing Chain: A: PDB Molecule:neuroepithelial cell-transforming gene 1 protein; PDBTitle: crystal structure of the rhogef domain of human neuroepithelial cell-2 transforming gene 1 protein 30 d1kz7a1 not modelled 100.0 26 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 31 d1foea1 not modelled 100.0 28 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 32 d1ntya1 not modelled 100.0 21 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 33 c3gf9A_ not modelled 100.0 24 PDB header:endocytosis Chain: A: PDB Molecule:intersectin 2; PDBTitle: crystal structure of human intersectin 2 rhogef domain 34 d1by1a_ not modelled 100.0 27 Fold:DBL homology domain (DH-domain) Superfamily:DBL homology domain (DH-domain) Family:DBL homology domain (DH-domain) 35 c2lqnA_ 100.0 25 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl 36 c2eyzA_ 100.0 25 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii 37 c1griA_ 100.0 28 PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 38 c2eyyA_ 100.0 20 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i 39 c2dvjA_ 99.9 24 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii 40 c3qwxX_ 99.9 21 PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174 41 c3qwyA_ not modelled 99.9 21 PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 42 c2l3gA_ not modelled 99.9 37 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: solution nmr structure of ch domain of rho guanine nucleotide exchange2 factor 7 from homo sapiens, northeast structural genomics consortium3 target hr4495e 43 d1ujoa_ not modelled 99.9 23 Fold:CH domain-like Superfamily:Calponin-homology domain, CH-domain Family:Calponin-homology domain, CH-domain 44 c1wymA_ not modelled 99.9 18 PDB header:structural protein Chain: A: PDB Molecule:transgelin-2; PDBTitle: solution structure of the ch domain of human transgelin-2 45 c1wyrA_ not modelled 99.9 32 PDB header:structural protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 6; PDBTitle: solution structure of the ch domain of human rho guanine2 nucleotide exchange factor 6 46 c1mv3A_ not modelled 99.9 18 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:myc box dependent interacting protein 1; PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc 47 c2l3sA_ not modelled 99.9 26 PDB header:structural protein Chain: A: PDB Molecule:autoinhibited crk protein; PDBTitle: structure of the autoinhibited crk 48 c1wypA_ not modelled 99.8 23 PDB header:structural protein Chain: A: PDB Molecule:calponin 1; PDBTitle: solution structure of the ch domain of human calponin 1 49 c2lg1A_ not modelled 99.8 10 PDB header:metal binding protein Chain: A: PDB Molecule:a-kinase anchor protein 13; PDBTitle: solution structure of the human akap13 ph domain and stabilizing dh2 helix 50 c1wynA_ not modelled 99.8 23 PDB header:structural protein Chain: A: PDB Molecule:calponin-2; PDBTitle: solution structure of the ch domain of human calponin-2 51 c1ov3A_ not modelled 99.8 28 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex 52 c1ng2A_ not modelled 99.8 31 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox 53 d1p2xa_ not modelled 99.8 21 Fold:CH domain-like Superfamily:Calponin-homology domain, CH-domain Family:Calponin-homology domain, CH-domain 54 c1p5sA_ not modelled 99.8 21 PDB header:cytokine Chain: A: PDB Molecule:ras gtpase-activating-like protein rng2; PDBTitle: structure and function of the calponin-homology domain of2 an iqgap protein from schizosaccharomyces pombe 55 d1h67a_ not modelled 99.8 26 Fold:CH domain-like Superfamily:Calponin-homology domain, CH-domain Family:Calponin-homology domain, CH-domain 56 c2rqrA_ not modelled 99.8 22 PDB header:protein binding Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex 57 c3i6xC_ not modelled 99.8 23 PDB header:calmodulin-binding, membrane protein Chain: C: PDB Molecule:ras gtpase-activating-like protein iqgap1; PDBTitle: crystal structure of the calponin homology domain of iqgap1 58 c2jxbA_ not modelled 99.8 16 PDB header:signaling protein complex Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain, PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex 59 d1ng2a2 not modelled 99.8 26 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 60 c3nmzD_ not modelled 99.7 23 PDB header:cell adhesion/cell cycle Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crytal structure of apc complexed with asef 61 c1x43A_ not modelled 99.7 28 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:sh3 domain grb2-like protein b1; PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1) 62 c2dlpA_ not modelled 99.7 23 PDB header:structural protein Chain: A: PDB Molecule:kiaa1783 protein; PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein 63 c1zlmA_ not modelled 99.7 40 PDB header:signaling protein Chain: A: PDB Molecule:osteoclast stimulating factor 1; PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor 64 c1x2qA_ not modelled 99.7 30 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2 65 c2ed0A_ not modelled 99.7 30 PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2) 66 d1ov3a2 not modelled 99.7 25 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 67 d1uj0a_ not modelled 99.7 31 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 68 c1k9aB_ not modelled 99.7 23 PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution 69 c2csqA_ not modelled 99.7 26 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:rim binding protein 2; PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2 70 c2l0aA_ not modelled 99.7 31 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 1; PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e 71 c2e5kA_ not modelled 99.7 21 PDB header:protein binding Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1; PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1 72 c2cubA_ not modelled 99.7 34 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1 73 d1k4us_ not modelled 99.7 27 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 74 d2dfka2 not modelled 99.7 17 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 75 c2oi3A_ not modelled 99.7 24 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1) 76 c2xmfA_ not modelled 99.7 34 PDB header:motor protein Chain: A: PDB Molecule:myosin 1e sh3; PDBTitle: myosin 1e sh3 77 d1i1ja_ not modelled 99.7 33 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 78 c2nwmA_ not modelled 99.7 41 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin 79 d1oota_ not modelled 99.7 44 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 80 c2ysqA_ not modelled 99.7 30 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9; PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9 81 c2yt6A_ not modelled 99.7 24 PDB header:cell cycle Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full- PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1 82 c1wx6A_ not modelled 99.7 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cytoplasmic protein nck2; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2 83 d1u5sa1 not modelled 99.7 26 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 84 c2df6A_ not modelled 99.7 42 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2 85 d1gcqa_ not modelled 99.7 34 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 86 c1x6gA_ not modelled 99.7 19 PDB header:signaling protein Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase; PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase. 87 c2kbtA_ not modelled 99.7 61 PDB header:signaling protein Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker, PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method 88 d1sema_ not modelled 99.7 35 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 89 c2d8hA_ not modelled 99.7 25 PDB header:unknown function Chain: A: PDB Molecule:sh3yl1 protein; PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1 90 c2cudA_ not modelled 99.7 20 PDB header:signaling protein Chain: A: PDB Molecule:src-like-adapter; PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap) 91 d1utia_ not modelled 99.7 35 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 92 d1wlpb2 not modelled 99.7 25 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 93 c2yupA_ not modelled 99.7 31 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the second sh3 domain of human vinexin 94 c1x6bA_ not modelled 99.7 24 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16; PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16 95 c2k6dA_ not modelled 99.7 34 PDB header:sh3 domain/ubiquitin Chain: A: PDB Molecule:sh3 domain-containing kinase-binding protein 1; PDBTitle: cin85 sh3-c domain in complex with ubiquitin 96 c2yunA_ not modelled 99.7 42 PDB header:protein transport Chain: A: PDB Molecule:nostrin; PDBTitle: solution structure of the sh3 domain of human nostrin 97 c2dbkA_ not modelled 99.7 37 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structures of the sh3 domain of human crk-like2 protein 98 c2dmoA_ not modelled 99.7 23 PDB header:signaling protein Chain: A: PDB Molecule:neutrophil cytosol factor 2; PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2) 99 d1udla_ not modelled 99.7 26 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 100 c2js0A_ not modelled 99.7 42 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of second sh3 domain of adaptor nck 101 d1uuea_ not modelled 99.7 31 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 102 d1wiea_ not modelled 99.7 28 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 103 c2yuoA_ not modelled 99.7 37 PDB header:signaling protein Chain: A: PDB Molecule:run and tbc1 domain containing 3; PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3 104 d1oeba_ not modelled 99.7 33 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 105 d1uhca_ not modelled 99.7 29 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 106 c2epdA_ not modelled 99.7 38 PDB header:protein binding Chain: A: PDB Molecule:rho gtpase-activating protein 4; PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4 107 c1wyxA_ not modelled 99.7 33 PDB header:cell adhesion Chain: A: PDB Molecule:crk-associated substrate; PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution 108 d1u06a1 not modelled 99.7 30 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 109 d1ov3a1 not modelled 99.7 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 110 c2dl4A_ not modelled 99.7 32 PDB header:signaling protein Chain: A: PDB Molecule:protein stac; PDBTitle: solution structure of the first sh3 domain of stac protein 111 d1ycsb2 not modelled 99.7 27 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 112 c1zx6A_ not modelled 99.7 35 PDB header:protein binding Chain: A: PDB Molecule:ypr154wp; PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain 113 d1gria2 not modelled 99.7 34 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 114 c2d1xD_ not modelled 99.7 40 PDB header:cell invasion Chain: D: PDB Molecule:cortactin isoform a; PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex 115 c2fpeB_ not modelled 99.7 26 PDB header:signaling protein Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein PDBTitle: conserved dimerization of the ib1 src-homology 3 domain 116 c2dm1A_ not modelled 99.7 91 PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the second sh3 domain of human2 protein vav-2 117 c3rnjA_ not modelled 99.7 30 PDB header:protein binding Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2) 118 c2ekhA_ not modelled 99.7 20 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structures of the sh3 domain of human kiaa0418 119 c2ebpA_ not modelled 99.7 31 PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1 120 c2dnuA_ not modelled 99.7 19 PDB header:structural genomics, structural protein Chain: A: PDB Molecule:sh3 multiple domains 1; PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human