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Job DescriptionQ92569
Confidence100.00%DateFri May 25 09:38:24 BST 2012
Rank8Aligned Residues233
% Identity76%Templatec2y3aB_
PDB info PDB header:transferaseChain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
Resolution3.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   184.....190.........200.........210.........220.........230.........240.........250.........260...
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Query Sequence  YHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEYIERFRREGNEKEIERIMMNYDKL
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Template Sequence  YHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEY. . . . . . LGNEKEMQRILLNSERL
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   443......450.........460.........470.........480.........490......... 500.........510......
 
   264.....270.........280.........290.........300.........310.........320.........330.........340...
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Query Sequence  KSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFI
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Template Sequence  KSRIAEIHESRTKLEQDLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLL. . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTT

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   523......530.........540.........550.........560.........570......
 
   344.....350.........360.........370.........380.........390.........400.........410.........420...
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Query Sequence  NEEDENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYS
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Template Sequence  . . . . . . . PHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYG
Template Known Secondary structure  .......GGGSSTTTB

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   609610.........620.........630.........640.........650.........660.........670.........680.
 
   424.....430.........440.........450.....
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Query Sequence  SLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQ
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Template Sequence  SLKELVLHYQHASLVQHNDALTVTLAHPVRAP
Template Known Secondary structure  STTSSS
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   682.......690.........700.........710...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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