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Job DescriptionP00519
Confidence100.00%DateSat Jun 16 10:22:56 BST 2012
Rank187Aligned Residues251
% Identity27%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   240.........250.........260.........270.........280.........290.........300.... .....310.....
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Query Sequence  TDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGV. . . . CTREPPFYIIT
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Template Sequence  RDITLLECVGKGRYGEVWRGSWQ. . GENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLIT
Template Known Secondary structure  TTTTT..T
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   206...210.........220........ .230.........240.........250.........260.........270.........280...
 
   316...320.........330.........340.........350......... 360.........370.........380.......
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Query Sequence  EFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF. . . . . . . . IHRDLAARNCLVGENHLVKVADFGLSRL
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Template Sequence  HYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
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   284.....290......... 300.........310.........320.........330.........340.........350.........360
 
   388. 390.........400.........410..... ....420.........430.........440.....
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Query Sequence  MT. . . GDTYTAHAGAKFPIKWTAPESLAYNK. . . . . . FSIKSDVWAFGVLLWEIATYGMSPYPGIDL. . . . . . . . . . . . .
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Template Sequence  HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDP
Template Known Secondary structure  TTTT








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   361........370.........380.........390.........400.........410...... ...420.........430.........
 
   446...450.........460... ......470.........480.........490......
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Query Sequence  . . SQVYELLEKDYRMERPEG. . . . . . CPEKVYELMRACWQWNPSDRPSFAEIHQAFETM
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Template Sequence  SFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
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   440.........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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