Return to main results Retrieve Phyre Job Id

Job DescriptionP00519
Confidence100.00%DateSat Jun 16 10:22:56 BST 2012
Rank113Aligned Residues243
% Identity48%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   232.......240.........250.........260.........270.........280.........290.........300.........310.
Predicted Secondary structure 
























Query SS confidence 















































































Query Sequence  YDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPF
Query Conservation                  

 
 

 
           



              
      
 
 


            
Alig confidence 






























.











.......




























Template Conservation       
          

 
 

 
 
    .    



 

 .......   

  
  
 




            
Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWR. GQYDVAIKMIKE. . . . . . . FIEEAKVMMNLSHEKLVQLYGVCTKQRPI
Template Known Secondary structure 
GGGB

GGGSTTSS
T.TT


.......
TT


TTB


SSSS
Template Predicted Secondary structure 







.


.......















Template SS confidence 















































































   392.......400.........410.........420.. .......430.... .....440.........450.........460...
 
   312.......320.........330.........340.........350.........360.........370.........380.........390.
Predicted Secondary structure 




































Query SS confidence 















































































Query Sequence  YIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGD
Query Conservation    
 
    
 
   
                          

     




  
 
       

 


 
      
Alig confidence 




















.



















































......
Template Conservation    
        
         .                                             
 
    ......
Template Sequence  FIITEYMANGCLLNYLREMRH. RFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . .
Template Known Secondary structure 

TT
GGG.


TT


S

SGGG
TT







......
Template Predicted Secondary structure 

















.
























......
Template SS confidence 















































































   471........480.........490. ........500.........510.........520.........530.........540...
 
   392.......400.........410.........420.........430.........440.........450.........460.........470.
Predicted Secondary structure 



































Query SS confidence 















































































Query Sequence  TYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYEL
Query Conservation                 


           



 
    
    
  
                                
Alig confidence  ...........




































































Template Conservation  ...........                  

 
 
    

 
                 
            
     
Template Sequence  . . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTI
Template Known Secondary structure  ...........GGG





TTS

TTTTS
TT





TTS
Template Predicted Secondary structure  ...........











































Template SS confidence 















































































   561........570.........580.........590.........600.........610.........620.........
 
   472.......480.........490.........500
Predicted Secondary structure 







Query SS confidence 




























Query Sequence  MRACWQWNPSDRPSFAEIHQAFETMFQES
Query Conservation          
  

                
Alig confidence 




























Template Conservation 
  

  

  


  


  
  

   
Template Sequence  MYSCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


Template Predicted Secondary structure 








Template SS confidence 




























   630.........640.........650........
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions