Job Description P00519 Confidence 100.00% Date Sat Jun 16 10:22:56 BST 2012 Rank 67 Aligned Residues 260 % Identity 37% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.					.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure																																.	.	.	.
Query SS confidence																																.	.	.	.
Query Sequence		D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	.	.	.	.	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E
Query Conservation																																.	.	.	.
Alig confidence																																.	.	.	.																.	.	.																											.
Template Conservation																																																			.	.	.																											.
Template Sequence		D	P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	I	.	.	.	A	D	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G	I	C	T	.	E
Template Known Secondary structure			T	T	S			G	G	G											S	S										T	T	S	S	S		S													.	.	.												T				T	T	B									.
Template Predicted Secondary structure																																																			.	.	.																											.
Template SS confidence
		866	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.				.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940		.
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	D	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M
Query Conservation
Alig confidence																							.
Template Conservation																							.
Template Sequence		N	G	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	.	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I
Template Known Secondary structure												T	T		B					T	G	G	.	G	T	T	T																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure																							.
Template SS confidence
		950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970		.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.
		389	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.																.	.	.	.	.	.	450	.	.	.
Predicted Secondary structure																																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	L	S	Q	V	Y	E	L	L	E
Query Conservation																																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																																.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																.
Template Sequence		E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V	N	T	L	K
Template Known Secondary structure			T	T					S			T	T			G	G	G																													T	.	T	T		G	G	G												S			G	G	G
Template Predicted Secondary structure																																																.
Template SS confidence
		1029	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.		.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.
		454	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L	L	K
Template Known Secondary structure		T	T							T	T												T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions