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Job DescriptionP00519
Confidence100.00%DateSat Jun 16 10:22:56 BST 2012
Rank191Aligned Residues222
% Identity25%Templatec3db8A_
PDB info PDB header:transferaseChain: A: PDB Molecule:polo-like kinase 1; PDBTitle: crystal structure of an activated (thr->asp) polo-like2 kinase 1 (plk1) catalytic domain in complex with compound3 041
Resolution3.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   240.........250.........260.........270.... .....280.........290.........300.........310.....
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Query Sequence  TDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLK. . . . EDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIIT
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Template Sequence  KRYMRGRFLGKGGFAKCYEITDMDTKEVFAGKVVPKSMLLKPHQKEKMSTEIAIHKSLDNPHVVGFHGFFEDDDFVYVVL
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   37..40.........50.........60.........70.........80.........90.........100.........110......
 
   316...320.........330.........340.........350.........360.........370.........380.........390.....
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Query Sequence  EFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTA
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Template Sequence  EICRRRSLLELHKRRKA. . VTEPEARYFMRQTIQGVQYLHNNRVIHRDLKLGNLFLNDDMDVKIGDFGLATKI. . . . . . .
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   117..120.........130... ......140.........150.........160.........170.........180.......
 
   396...400.........410.........420.........430.........440.........450.........460.........470.....
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Query Sequence  HAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRAC
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Template Sequence  . . . . . . . . . . . . . . . . . . . . HSFEVDIWSLGCILYTLLV. GKPPFETSCLKETYIRIKKNE. YSVPRHINPVASALIRRM
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   214.....220.........230.. .......240.........250... ......260.........270.
 
   476...480.........490..
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Query Sequence  WQWNPSDRPSFAEIHQA
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Template Sequence  LHADPTLRPSVAELLTD
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   272.......280........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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