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Job DescriptionP00519
Confidence100.00%DateSat Jun 16 10:22:56 BST 2012
Rank209Aligned Residues249
% Identity37%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240. ........250.........260..... ....270..... ....280.........290.........300.....
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Query Sequence  DKWEMERTD. . ITMKHKLGGGQYGEVYEGVWKKYS. . . LTVAVKTLKE. . DTMEVEEFLKEAAVMKEIKHPNLVQLLGVC
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC
Template Known Secondary structure  TTTB

STT

SSSTTT

S
S
STTSTT


TTB



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   1067..1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140......
 
   306...310.........320.........330.........340.........350.........360.........370.........380.....
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Query Sequence  TREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS
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Template Sequence  LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADFLPV
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SS



TT
B
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BTT


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GGG
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G
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   1147..1150.........1160.........1170.........1180.........1190.........1200.........1210.........1220......
 
   386...390.........400.........410.........420.........430.........440.........450.........460.....
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Query Sequence  RLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCP
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Template Sequence  K. . . . . . . . . . . . . . . . . . WMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCP
Template Known Secondary structure  G..................GS




TTS

S
TTS
SS
TT





TT

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   1248 .1250.........1260.........1270.........1280.........1290.........1300.........
 
   466...470.........480.........490.........
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Query Sequence  EKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE
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Template Sequence  DPLYEVMLKCWHPKAEMRPSFSELVSRISAIFST
Template Known Secondary structure  T
SSGGGS

T
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   1310.........1320.........1330.........1340...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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